Cellular & Molecular Immunology, Published online: 30 April 2026; doi:10.1038/s41423-026-01418-7De novo engineered disulfide bond supersedes native interchain linkage to enhance TCR pairing and anti-tumor efficacy in T cell therapy
Cellular & Molecular Immunology, Published online: 30 April 2026; doi:10.1038/s41423-026-01412-zShort-, medium-, versus long-chain fatty acids: mechanisms of immunomodulation and disease pathogenesis
Cellular & Molecular Immunology, Published online: 30 April 2026; doi:10.1038/s41423-026-01418-7De novo engineered disulfide bond supersedes native interchain linkage to enhance TCR pairing and anti-tumor efficacy in T cell therapy
Cellular & Molecular Immunology, Published online: 27 April 2026; doi:10.1038/s41423-026-01421-yInhibition of glycosphingolipid synthesis overcomes the steric hindrance of CD30 N-glycans to augment CD30-targeted immunotherapeutic e…
Cellular & Molecular Immunology, Published online: 24 April 2026; doi:10.1038/s41423-026-01416-9Commentary: Yin and Yang of MAITs in HCC: balancing type 1 vs. type 17 signaling
Cellular & Molecular Immunology, Published online: 22 April 2026; doi:10.1038/s41423-026-01417-8Interleukin enhancer binding factor 3 exacerbates cardiac inflammation and injury following myocardial infarction by inhibiting Lys48-l…
Cellular & Molecular Immunology, Published online: 22 April 2026; doi:10.1038/s41423-026-01413-yEZH2 and intracellular Ca2+ signals interdependently coordinate alloreactive and CAR-T-cell responses
Cellular & Molecular Immunology, Published online: 22 April 2026; doi:10.1038/s41423-026-01415-wConstruction of an engineered Escherichia coli strain with enhanced intestinal colonization and anti-inflammatory efficacy in colitis
Cellular & Molecular Immunology, Published online: 22 April 2026; doi:10.1038/s41423-026-01420-zRegulatory heme: a mitochondria-to-nucleus messenger of CD8+ T-cell exhaustion
Cellular & Molecular Immunology, Published online: 10 April 2026; doi:10.1038/s41423-026-01408-9Hepatocyte-derived LRG1 primes the liver for metastasis and impairs immunotherapy
Cellular & Molecular Immunology, Published online: 07 April 2026; doi:10.1038/s41423-026-01411-0Lipid metabolism reprogramming shapes the immune landscape in the tumor microenvironment
Cellular & Molecular Immunology, Published online: 02 April 2026; doi:10.1038/s41423-026-01398-8Persistent IFN-I signaling inhibits mitochondrial oxidative metabolism in CD8+ T cells during HIV-1 infection under cART
Cellular & Molecular Immunology, Published online: 02 April 2026; doi:10.1038/s41423-026-01407-wAcute stress alleviates type 2 lung inflammation by restricting ILC2s through corticosterone-glucocorticoid receptor signaling
Cellular & Molecular Immunology, Published online: 01 April 2026; doi:10.1038/s41423-026-01410-1SPT6 maintains epidermal homeostasis by inhibiting an NF-κB-positive feedback loop to prevent excessive inflammation
Cellular & Molecular Immunology, Published online: 19 March 2026; doi:10.1038/s41423-026-01401-2Reprogramming the immune orchestra for glioblastoma: oncolytic viruses and the B-cell connection
Cellular & Molecular Immunology, Published online: 17 March 2026; doi:10.1038/s41423-026-01397-9The type-I interferon priming signal balances antibacterial and antitumor trained immunity in alveolar macrophages
Cellular & Molecular Immunology, Published online: 16 March 2026; doi:10.1038/s41423-026-01399-7RNA-binding proteins Zfp36l1 and Zfp36l2 protect against premature thymic involution
Cellular & Molecular Immunology, Published online: 04 March 2026; doi:10.1038/s41423-026-01396-wOncolytic virus M1 reinvigorates CD8+ T-cell immunity against glioblastoma through B-cell-dependent antigen cross-presentation in the s…
Cellular & Molecular Immunology, Published online: 04 March 2026; doi:10.1038/s41423-026-01391-1Lytic IFNγ is stored in cytotoxic granules and coreleased with granzyme B to mediate cytotoxic T lymphocyte killing
Cellular & Molecular Immunology, Published online: 04 March 2026; doi:10.1038/s41423-026-01395-xTofacitinib repairs inflammation and mitochondrial dysregulation in GM-CSF-reprogrammed RA macrophages
Cellular & Molecular Immunology, Published online: 24 February 2026; doi:10.1038/s41423-026-01392-0B cells maintain the homeostasis of splenic marginal zone antigen-presenting cells to promote the antiviral CD8+ T-cell response
Cellular & Molecular Immunology, Published online: 24 February 2026; doi:10.1038/s41423-026-01394-yAuthor Correction: NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology
Cellular & Molecular Immunology, Published online: 30 January 2026; doi:10.1038/s41423-026-01386-yTWEAK receptor (Fn14) exacerbates TNF-α-induced inflammation in rheumatoid arthritis synovial fibroblasts and influences response to …
Cellular & Molecular Immunology, Published online: 27 January 2026; doi:10.1038/s41423-026-01389-9Obesity disrupts ILC2 metabolic and functional homeostasis by inhibiting mTORC1 signaling
Cellular & Molecular Immunology, Published online: 27 January 2026; doi:10.1038/s41423-026-01387-xTackling cuproptosis: from metabolic rewiring to therapeutic exploitation in cancer
Cellular & Molecular Immunology, Published online: 14 January 2026; doi:10.1038/s41423-025-01383-7tRNA m1A modification orchestrates STING translation in macrophages to enhance antitumor immunity and CAR-macrophage immunotherapy
Cellular & Molecular Immunology, Published online: 13 January 2026; doi:10.1038/s41423-025-01375-7Excitatory amino acid transporters support mast cell degranulation via α-KG-mediated methylation of Spp1
Cellular & Molecular Immunology, Published online: 13 January 2026; doi:10.1038/s41423-025-01380-wNeutrophils as critical orchestrators of chronic inflammation
Cellular & Molecular Immunology, Published online: 06 January 2026; doi:10.1038/s41423-025-01384-6Epigenetics control lineage decisions during hematopoiesis of innate lymphocytes
Cellular & Molecular Immunology, Published online: 06 January 2026; doi:10.1038/s41423-025-01382-8Prion-like MAVS fibrils stitch mitochondria to promote a rapid antiviral response
Cellular & Molecular Immunology, Published online: 06 January 2026; doi:10.1038/s41423-025-01372-wFrom splicing noise to therapeutic signaling: RCAN1–4 as a neoepitope in glioblastoma
Cellular & Molecular Immunology, Published online: 01 January 2026; doi:10.1038/s41423-025-01352-0MDA5 regulates BCR signaling and B-cell function via NF-κB-mediated DNM1
Cellular & Molecular Immunology, Published online: 24 December 2025; doi:10.1038/s41423-025-01376-6CD160+ intraepithelial lymphocytes and CCRL2+ macrophages drive differential repair in cardiac and liver injuries
Cellular & Molecular Immunology, Published online: 23 December 2025; doi:10.1038/s41423-025-01360-0C/EBPβ-induced alternative splicing of RCAN1 generates a potent TCR-T target in mesenchymal glioblastoma
Cellular & Molecular Immunology, Published online: 19 December 2025; doi:10.1038/s41423-025-01378-4Regulation of T cell exhaustion and stemness: molecular mechanisms and implications for cancer immunotherapy
Cellular & Molecular Immunology, Published online: 16 December 2025; doi:10.1038/s41423-025-01379-3Inflammation and cell death drive Monkeypox-induced viral pathogenesis
Cellular & Molecular Immunology, Published online: 10 December 2025; doi:10.1038/s41423-025-01373-9Cis- and trans-binding chimeric costimulatory receptors enhance T-cell fitness and tumor control
Cellular & Molecular Immunology, Published online: 08 December 2025; doi:10.1038/s41423-025-01374-8MST1 bridges LYN and SHP-1 to suppress FcεRI-mediated mast cell activation and allergic responses
Cellular & Molecular Immunology, Published online: 08 December 2025; doi:10.1038/s41423-025-01371-xPA28γ-containing tumor-derived exosomes promote T-cell dysfunction in head and neck squamous cell carcinoma
Cellular & Molecular Immunology, Published online: 03 December 2025; doi:10.1038/s41423-025-01364-wMORF’ing of cGAS-STING to precisely tune radiosensitization and immune activation in hepatocellular carcinoma
Cellular & Molecular Immunology, Published online: 03 December 2025; doi:10.1038/s41423-025-01366-8Dysregulation of innate immune sensors and autoinflammation: insights from an NLRC4 mouse AIFEC model
Cellular & Molecular Immunology, Published online: 25 November 2025; doi:10.1038/s41423-025-01369-5DIS3 licenses B cells for plasma cell differentiation in humans
Cellular & Molecular Immunology, Published online: 21 November 2025; doi:10.1038/s41423-025-01368-6Microglia across evolution: from conserved origins to functional divergence
Cellular & Molecular Immunology, Published online: 18 November 2025; doi:10.1038/s41423-025-01370-yAuthor Correction: Not marginal but central: type I interferons unleash marginal zone B cells in Sjögren’s disease
Cellular & Molecular Immunology, Published online: 14 November 2025; doi:10.1038/s41423-025-01363-xFOXO1-driven metabolic reprogramming of hematomal CD8+ T cells drives the expansion of perihematomal edema following intracerebral h…
Cellular & Molecular Immunology, Published online: 12 November 2025; doi:10.1038/s41423-025-01367-7AIM2 drives inflammatory cell death and monkeypox pathogenesis
Cellular & Molecular Immunology, Published online: 05 November 2025; doi:10.1038/s41423-025-01351-1Targeting MORF4L1-mediated DNA repair potentiates RT-induced antitumor immunity via cGAS-STING activation in hepatocellular carcinoma
Cellular & Molecular Immunology, Published online: 29 October 2025; doi:10.1038/s41423-025-01361-zYDJC restrains Th1 cell differentiation by blocking SREBP2-mediated cholesterol biosynthesis to alleviate mucosal inflammation in inf…
Cellular & Molecular Immunology, Published online: 27 October 2025; doi:10.1038/s41423-025-01353-zNot marginal but central: type I interferons unleash marginal zone B cells in Sjögren’s disease
Cellular & Molecular Immunology, Published online: 20 October 2025; doi:10.1038/s41423-025-01355-xAn animal model of NLRC4-associated autoinflammation and infantile enterocolitis reveals novel therapeutic strategies
Cellular & Molecular Immunology, Published online: 09 October 2025; doi:10.1038/s41423-025-01348-wDissection of the trans-endocytosis and signal inhibition functions of CTLA-4 through the study of a disease-associated Y139C mutation
Cellular & Molecular Immunology, Published online: 09 October 2025; doi:10.1038/s41423-025-01354-yMolecular mechanisms and regulation of inflammasome activation and signaling: sensing of pathogens and damage molecular patterns
Cellular & Molecular Immunology, Published online: 03 October 2025; doi:10.1038/s41423-025-01350-2Correction: Cholesterol promotes autoimmune pathology through T follicular helper cells
Cellular & Molecular Immunology, Published online: 24 September 2025; doi:10.1038/s41423-025-01347-xMacrophages regulate PD-1 and CTLA-4 expression on ILC2s and their responsiveness in the tumor microenvironment
Cellular & Molecular Immunology, Published online: 22 September 2025; doi:10.1038/s41423-025-01342-2Liver immunology: new insights from cutting-edge technologies
Cellular & Molecular Immunology, Published online: 18 September 2025; doi:10.1038/s41423-025-01340-4The role of the IL-9‒NLRP3 axis in insulin resistance and adipose tissue inflammation during diet-induced obesity
Cellular & Molecular Immunology, Published online: 17 September 2025; doi:10.1038/s41423-025-01343-1Infiltrating macrophages replace Kupffer cells and play diverse roles in severe alcohol-associated hepatitis
Cellular & Molecular Immunology, Published online: 10 September 2025; doi:10.1038/s41423-025-01346-yThe STING/type I interferon axis drives the interplay between marginal zone B cells and T follicular helper cells in Sjögren’s dise…
Cellular & Molecular Immunology, Published online: 10 September 2025; doi:10.1038/s41423-025-01335-1Restoration of the peace in autoimmune disease: tired of fighting?
Cellular & Molecular Immunology, Published online: 10 September 2025; doi:10.1038/s41423-025-01345-zEndothelial cell–ILC3 crosstalk via the ET-1/EDNRA axis promotes NKp46+ILC3 glycolysis to alleviate intestinal inflammation
Cellular & Molecular Immunology, Published online: 08 September 2025; doi:10.1038/s41423-025-01344-0Intestinal taurine acts as a novel immunometabolic modulator of IBD by degrading redundant mitochondrial RNA
Cellular & Molecular Immunology, Published online: 08 September 2025; doi:10.1038/s41423-025-01339-xGut-derived indole propionic acid alleviates liver fibrosis by targeting profibrogenic macrophages via the gut‒liver axis
Cellular & Molecular Immunology, Published online: 08 September 2025; doi:10.1038/s41423-025-01336-0FBXW7 is a multifaceted regulator of the innate immune response to DNA viruses
Cellular & Molecular Immunology, Published online: 29 August 2025; doi:10.1038/s41423-025-01338-yMacrophage-derived VISTA engages with LRIG1 and hinders gut epithelial repair in colitis
Cellular & Molecular Immunology, Published online: 29 August 2025; doi:10.1038/s41423-025-01337-zFunctional importance of bile acid-FXR signaling in neonatal immunity and disease
Cellular & Molecular Immunology, Published online: 26 August 2025; doi:10.1038/s41423-025-01330-6Author Correction: SMAD7 expression in CAR-T cells improves persistence and safety for solid tumors
Cellular & Molecular Immunology, Published online: 20 August 2025; doi:10.1038/s41423-025-01331-5SARDH in the 1-C metabolism sculpts the T-cell fate and serves as a potential cancer therapeutic target
Cellular & Molecular Immunology, Published online: 14 August 2025; doi:10.1038/s41423-025-01325-3The cytokine CSBF inhibits the IL-17A and TNF-α inflammatory pathways via SUSD2-ACT1 in keratinocytes and alleviates IMQ-induced psori…
Cellular & Molecular Immunology, Published online: 14 August 2025; doi:10.1038/s41423-025-01333-3Beyond the gut: decoding the gut–immune–brain axis in health and disease
Cellular & Molecular Immunology, Published online: 08 August 2025; doi:10.1038/s41423-025-01328-0Author Correction: Multiscale dynamic immunomodulation by a nanoemulsified Trojan-TLR7/8 adjuvant for robust protection against hetero…
Cellular & Molecular Immunology, Published online: 06 August 2025; doi:10.1038/s41423-025-01326-2The gut microbiota in cancer immunity and immunotherapy
Cellular & Molecular Immunology, Published online: 06 August 2025; doi:10.1038/s41423-025-01332-4Provocation and palliation—the dual roles of dermal white adipose tissue in neutrophilic skin inflammation
Cellular & Molecular Immunology, Published online: 28 July 2025; doi:10.1038/s41423-025-01329-zPANoptosis in cancer: bridging molecular mechanisms to therapeutic innovations
Cellular & Molecular Immunology, Published online: 23 July 2025; doi:10.1038/s41423-025-01318-2Notch2−expressing CD4+ T cells attain immunoregulatory functions during autoimmune inflammation
Cellular & Molecular Immunology, Published online: 14 July 2025; doi:10.1038/s41423-025-01323-5The role of exosomes in immunopathology and potential therapeutic implications
Cellular & Molecular Immunology, Published online: 14 July 2025; doi:10.1038/s41423-025-01311-9CD8+GZMK+CD27+CCR7+ T cells mobilized by splenic sympathetic nerves aggravate brain ischemia‒reperfusion injury via CCL19-positive endot…