Surprising mechanism of lupus kidney damage identified
A team defined key cells behind severe kidney damage in lupus. The research can inform future antibody therapies.
Immune System News -- ScienceDaily
New vaccine against cervical cancer combines prophylactic and therapeutic activity
A vaccine against cancer-causing human papillomaviruses (HPV) is intended to help increase the rate of HPV vaccinations, particularly in developing countries. Scientists developed a completely new vaccination concept for this purpose. The vaccine is in…
Immune cell regulator discovery could lead to treatments for arthritis and severe COVID
The discovery of a new regulator affecting immune cells could lead to new treatments to reduce inflammation in diseases including arthritis and severe COVID-19.
Two new studies show how immunotherapies collaborate to boost T cell responses in melanoma
Two recent studies uncover how immunotherapies targeting the immune checkpoints PD1 and LAG3 work together to activate immune responses. The findings shed light on why combination therapies targeting both checkpoints can improve outcomes for melanoma p…
Clinical trial shows JAK inhibitor improves multiple autoimmune conditions in patients with Down syndrome
An unprecedented study reveals strategy to decrease the burden of alopecia areata, atopic dermatitis, psoriasis and other autoimmune conditions.
Peptide boronic acids: New prospects for immunology
A chemical process is the first to make it possible to quickly and easily produce modified peptides with boronic acids. These biologically active peptide boronic acids open up new possibilities in the young research field of synthetic immunology and co…
Could targeting metabolism treat blood clots in antiphospholipid syndrome?
Targeting glycolysis can help lower neutrophil extracellular trap formation in antiphospholipid syndrome.
Pre-surgical antibody treatment might prevent heart transplant rejection
Anti-rejection regimens currently in use are broad immunosuppressive agents that make patients susceptible to infections. By using specific antibodies, it may be possible to just block the inflammation that leads to rejection but leave anti-microbial i…
An appetizer can stimulate immune cells’ appetite, a boon for cancer treatments
The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer. Chief among this force is the macrophage, a white blood cell that surveils tissues and consumes pathogens, debris, dead cells, and can…
NK cells expressing interleukin-21 show promising antitumor activity in glioblastoma cells
Natural killer (NK) cells engineered to express interleukin-21 (IL-21) demonstrated sustained antitumor activity against glioblastoma stem cell-like cells (GSCs) both in vitro and in vivo, according to new research.