New immunotherapy could treat cancer in the bone
A new type of immunotherapy has shown promising preclinical results against a bone cancer called osteosarcoma, as part of a study in mice.
A new type of immunotherapy has shown promising preclinical results against a bone cancer called osteosarcoma, as part of a study in mice.
A team of cancer researchers has discovered a new subset of T cells that may improve the outcome for patients treated with T-cell therapies.
A multidisciplinary research team has revealed that the circadian clock — the biological pacemaker that governs daily rhythms in physiological processes, including immune functions — can be leveraged to enhance the efficacy of checkpoint inhibitor ca…
Researchers have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selec…
Researchers have identified the genetic basis behind certain severe immunodeficiencies in newborns, paving the way for potential screening and emerging therapies.
Researchers discovered that people who experienced symptomatic breakthrough infections develop T cells that are better at recognizing and targeting SARS-CoV-2, including the Omicron and Delta variants. The researchers describe this increased protection…
Researchers have discovered a peptide in human RNA that regulates inflammation and may provide a new path for treating diseases such as arthritis and lupus. The team used a screening process based on the powerful gene-editing tool CRISPR to shed light …
The stress of heart failure is remembered by the body and appears to lead to recurrent failure, along with other related health issues, according to new research. Researchers have found that heart failure leaves a ‘stress memory’ in the form of changes…
Researchers have developed a new strain of vaccinia virus, which can replicate in tumor cells while maintaining increased immunogenicity. Specifically, it can to induce so-called immunogenic cell death in tumor cells.
The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers. Emerging data now show that inhibition of a specific metabolic pathway in infected cells can diminish latent infection and therefore the risk of downstream disease.