Role of ‘hunger hormone’ receptor in obesity-realted chronic inflammation
A team of scientists has made an important discovery that could lead to a novel treatment for obesity and obesity-associated diseases or conditions.
Immune System News -- ScienceDaily
Complement system causes cell damage in long Covid
Long Covid patients suffer from chronic symptoms such as fatigue or shortness of breath. As researchers have discovered, this is to some extent due to a part of our immune system called the complement system. The study identified a pattern in the blood…
Remodeling the immune system to fight tuberculosis
Tuberculosis, caused by the bacterium Mycobacterium tuberculosis (Mtb) kills upwards of 1.6 million people a year, making it one of the leading causes of death by an infectious agent worldwide — and that number is only growing larger. How, exactly, Mt…
New vaccine design uses immunity against influenza to offer faster protection against emerging pathogens
Imagine a vaccine that speeds up the production of antibodies against SARS-CoV-2, the virus that spreads COVID-19. A research team has developed such a vaccine by using preexisting immunity to a separate virus (the influenza virus) to help kickstart th…
A new targeted treatment calms the cytokine storm
Researchers have discovered a novel treatment to relieve cytokine release syndrome (CRS), a life-threatening inflammation triggered by a serious infection or severe burn. Treatment with a short-acting antibody reduces the inflammatory effects of interl…
Researchers identify key characteristics associated with improved CAR T outcomes in large B cell lymphoma
Axi-cel CAR T targets the CD19 molecule on large B-cell lymphoma cells. The ZUMA-7 trial demonstrated that axi-cel reduced the risk of disease progression, the need for new therapy, or death by 60% compared to standard therapy. Despite these positive o…
How gum disease aggravates chronic obstructive pulmonary disease
A new study shows how periodontitis, an oral disease, activates immune cells associated with aggravated progression of COPD.
Incurable autoimmune disease Systemic Lupus Erythematosus (SLE): New genetic findings open up perspectives for future therapeutic approaches
Systemic lupus erythematosus (SLE) is an autoimmune disease, in which the immune system that normally protects the body from invading microbes turns against the body’s own cells. Researchers studied four patients from two families who developed symptom…
CD4+ T cell patterns linked to autoimmune disorders
Researchers found that CD4+ T cells can be classified into 18 categories and 12 distinct gene programs, and that characteristic changes in CD4+ T cell profiles are associated with autoimmune disease, sex, and aging. Analysis of these distinctive immune…