Certain RNA modifications could contribute to the development of autoimmune disorders
New research published in Nature has uncovered powerful evidence that may explain why a new chemical modification of RNA is made in cells.
Diseases, Conditions, Syndromes
Preexisting anemia may make malaria worse, research finds
New research from The University of Toledo suggests that individuals with anemia may have a significantly higher risk of developing severe complications if they contract malaria. The findings were published this month in the peer-reviewed journal Infec…
Key protein Gfi1 found to regulate exhausted T cells in cancer and infection
Killer immune cells destroy cancer cells and cells infected by virus. These CD8+ T cells are activated after detection of viral infection or growth of “non-self” tumor cells. However, in chronic viral infection and cancer, the killer cells often lapse …
The contagion scale: Which diseases spread fastest?
When the COVID pandemic hit, many people turned to the eerily prescient film “Contagion” (2011) for answers—or at least for catharsis. Suddenly, its hypothetical plot felt all too real. Applauded for its scientific accuracy, the film offered more than …
Final clinical trial data for advanced kidney cancer treatment shows efficacy of two-drug combination
A two-drug combination for treating advanced kidney cancer has shown sustained and durable clinical benefit in more than five years of follow-up, according to a study published in Nature Medicine.
Discovery shows rogue protein fuels Hodgkin lymphoma growth
A new discovery made by researchers from The Australian National University (ANU) could lead to smarter, more effective treatments for Hodgkin lymphoma, a common blood cancer.
Aging dampens lupus by reducing overactive immune genes in older adults
UCSF researchers have found that certain antiviral genes become less active over time in lupus, revealing why some patients see their symptoms fade as they age.
Inflammation and nutrition-based scores tied to prognosis of low-risk myelodysplastic syndrome
The Prognostic Nutritional Index (PNI) and systemic oxidative stress (SOS) score are independently associated with poorer prognosis of low-risk myelodysplastic syndrome (MDS), according to a study published online July 4 in the Journal of Clinical Medi…
Allogeneic HCT feasible in older patients with myelodysplastic syndrome
Allogeneic hematopoietic cell transplantation (allo-HCT) is feasible in older patients with myelodysplastic syndrome (MDS), according to a study published online June 26 in the European Journal of Haematology.
Unique immune cell linked to aggressive leukemia may lead to improved treatment outcomes
A new study by Indiana University School of Medicine researchers has revealed a breakthrough in the fight against acute myeloid leukemia, one of the most aggressive and fatal blood cancers in adults. The discovery of a previously unrecognized immune ce…