A research team has identified the impact of stem cell infusion timing on the incidence and severity of acute graft-versus-host disease (aGVHD) in allogeneic hematopoietic stem cell transplantation (allo-HSCT), highlighting the role of the recipient’s …
As scientists, we often think we understand a virus—its structure, its tricks, the way it moves through the body. But every once in a while, we stumble upon something unexpected—something that completely changes the way we see an infection.
Early diagnosis of COPD, chronic obstructive pulmonary disease, increases the quality of life of the patient and the efficacy of available treatments. Researchers at Karolinska Institutet have now shown that material from nasal lavage provides a basis …
Most humans have long-lived infections in various tissues—including in the nervous system—that typically do not result in disease. The microbes associated with these infections enter a latent stage during which they quietly hide in cells, playing the l…
Research from Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago strongly suggests that Kawasaki disease is caused by a single respiratory virus that is yet to be identified. Findings contradict the theo…
COVID infection has been linked to a higher risk of autoimmune disorders, including rheumatoid arthritis and type 1 diabetes. But why the virus might cause the body’s immune system to go haywire remains unknown, making it difficult to develop therapies…
Zika virus and dengue virus are very close relatives. Both are mosquito-borne flaviviruses, and both specialize in infecting a host’s dendritic cells.
During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that are expressed by cells of the body. If not, the immune system can mistakenly attack its own cells, ca…
An immune system defect makes affected individuals vulnerable to severe viral diseases such as influenza or COVID-19. It is caused by the body’s own antibodies, which inhibit important defense proteins known as type I interferons. UZH researchers have …
Imagine a previously unknown bug—new to our immune defenses—that suddenly emerged and rapidly spread all over the globe, causing the deaths of millions and an economic breakdown due to the interruption of work in virtually every country.
