Antiretroviral treatments for HIV (human immunodeficiency virus) have been extremely successful in extending life expectancy and reducing transmission. But one major challenge has so far prevented researchers from developing a cure: HIV likes to hide.
More than 40 million people worldwide are living with HIV-1, which continues to be a major global health challenge due to its ability to persist silently within immune cells, evading complete eradication. Researchers at LKS Faculty of Medicine, the Uni…
In an important discovery, researchers from Florida Atlantic University’s Charles E. Schmidt College of Medicine have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body’s natural defe…
Lipids are the fatty molecules that make up cellular membranes, creating a protective barrier that regulates what enters and exits the cell. Until recently, scientists believed antibodies couldn’t safely target lipids without risking harm to healthy ti…
Tackling HIV continues to be a major public health challenge, mainly because the persistence of viral reservoirs means that people living with HIV need to take lifelong antiretroviral treatment. But some individuals, known as “post-treatment controller…
Long-acting injectable antiretroviral therapy (ART) can be administered at home to persons living with HIV as safely and effectively by a health care professional as in the clinic, with equally high patient satisfaction rates, according to a new study …
If the past four decades have taught us anything about HIV, it’s to adjust our expectations—despite enormous progress in controlling the virus, no treatment can yet completely eradicate HIV once it has taken hold. But promising results from a recent cl…
Mount Sinai researchers have developed a method to uncover the hidden immune cells that harbor the human immunodeficiency virus (HIV), a discovery that brings medical experts one step closer to a cure for the infection affecting nearly 40 million peopl…
Researchers led by Imperial have unveiled primary trial results that show encouraging advances in HIV treatment driven by immune-based therapies.
A new study reveals that a significant proportion of people living with HIV (PWH) on long-term antiretroviral therapy remain at risk of immune and metabolic complications despite successful viral suppression. The findings highlight a pressing need for …
