Immune cells in human lung tissue may drive the development of autoimmune disease
A massive analysis of immune cells in human tissue is yielding clues to the root causes of lung and autoimmune diseases.
Medical Xpress
Breast milk protein osteopontin may shield infants from respiratory infections
QIMR Berghofer researchers have found how breast milk supports infant immunity via a protein called osteopontin. The study also identifies a potential way of mimicking this protective effect in baby formula. The findings, published today in the journal…
New insights into genetic architecture of a rare systemic inflammatory disease in East Asian populations
Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic inflammatory disease characterized by eosinophilia, an abnormal increase in eosinophils—a type of white blood cell—and inflammation of small blood vessels across multiple organs, which …
Lupus-linked immune misdirection could leave patients vulnerable to staph infections
Microbiology researchers from the University of Tennessee, Knoxville, have discovered why patients with the autoimmune disease lupus are susceptible to serious bacterial infections. Their new study published in Cell Press Blue shows that lupus-associat…
A third of patients with chronic rhinosinusitis with nasal polyps exhibit anxiety symptoms
A considerable proportion of patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit anxiety symptoms, according to a study published in the Journal of Inflammation Research.
Exacerbation risk profiles vary with house dust mite sensitization in pediatric asthma
For children with asthma, exacerbation risk is associated with distinct profiles depending on house dust mite (HDM) sensitization status, according to a study published online July 16 in the International Journal of Occupational Medicine and Environmen…
Press-needle therapy shows potential for pediatric allergic rhinitis
For children with allergic rhinitis (AR), press-needle therapy, especially in addition to medication, is potentially effective in improving clinical response, symptoms and quality of life, according to a review published in the September issue of the I…
Mighty mitochondria: Scientists uncover new role for fighting bacterial infections, including drug-resistant superbugs
Beyond the nucleus, no other organelle in eukaryotic cells captures the public’s imagination quite like mitochondria: They are the engines of cellular energy production; they possess their own DNA, and they are passed from generation to generation from…
Long COVID and immune ‘soldier’ cells: Q&A
Extreme fatigue, a racing pulse, shortness of breath, brain fog, aching joints—the symptoms of long COVID can vary widely, change unpredictably and be difficult to recognize as signs of the condition. Long COVID also remains difficult to treat, as no s…
Leaky gut might make food allergies worse
A “leaky gut” might increase the severity of food allergies, according to new research conducted in mice and published in The Journal of Immunology. The researchers found that changes to the gut microbiome in mice were linked to increased intestinal pe…