A type of rare T cell triggers a cascade of signals amplifying inflammation and ultimately leading to liver fibrosis, according to a new study from Julius Maximilian University of Würzburg published in Nature Communications. Over time, this process con…
Macrophages, key regulators of tissue health and immune defense, are among the most abundant immune cells in solid tumors. Their role in cancer has been difficult to define because even closely related macrophage populations can have very different, an…
B cells are white blood cells that form a core part of the body’s adaptive immune system, enabling it to recognize specific infections, remember them, and mount a targeted response by producing antibodies. A recent study published in Cell has found tha…
Patients who developed myocarditis within the first month of receiving immune checkpoint inhibitor therapy were more likely to die of myocarditis, and myocarditis-specific fatality was more common in patients who experienced co-occurring myositis and m…
Some people living with HIV develop antibodies capable of neutralizing many different strains of the virus. New research links this to immune responses that occur early in infection. The findings, published in PLOS Pathogens, come from an international…
A new study published in The Journal of Immunology by researchers at the Josep Carreras Leukaemia Research Institute (IJC) has uncovered a crucial biological “off switch” in diffuse large B cell lymphoma (DLBCL), the most common and one of the most agg…
While modern life includes many conveniences, humans are still incessantly exposed to a variety of metabolic stresses we have never experienced before. Our immune systems are constantly trying to protect us, and CD8⁺ T cells in particular—also known as…
Cannabis is no longer viewed solely as a recreational substance; it is increasingly recognized for its therapeutic potential. In many parts of the world, laws have evolved to include the use of cannabis for medical purposes. The medical community hasn’…
The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack the complex cellular machinery of the human body. Yet, even after decades of research on how the virus replicates and persists…
Deep in the lungs, resident memory B cells stand guard against influenza reinfection—but whether they remain there may depend on how strongly they are signaled through their own receptors. New research using an animal model of influenza infection provi…
