Swelling caused by brain cancer is a serious problem that can lead to serious side effects and even death. While controlling swelling is important, a new study shows that a commonly prescribed anti-swelling drug suppresses the immune system for weeks a…
Manipulating the immune system to treat cancer has generated phenomenal responses in some patients, including complete cures, but those responses do not last for everyone. For example, chimeric antigen receptor (CAR) T–cell immunotherapy causes an init…
Researchers at the University of Texas MD Anderson Cancer Center have developed a novel antibody-toxin conjugate (ATC) designed to stimulate immune-mediated eradication of tumors. According to preclinical results published in Nature Cancer, the new app…
Researchers have discovered and analyzed a rare but serious side effect of an innovative form of blood cancer therapy. The scientists from the University of Leipzig Medical Center, the Fraunhofer Institute for Cell Therapy and Immunology (IZI) and the …
The concept of using vaccines to treat cancers has been around for several decades. A vaccine was first approved for prostate cancer in 2010, and another was approved in 2015 for melanoma. Since then, many therapeutic—as opposed to preventive—cancer va…
Renal + Urology News highlighted research led by the University of Cincinnati’s Alberto Martini, MD, that found using antihistamines in patients receiving second-line immunotherapy (IO) for bladder cancer may improve outcomes.
Mayo Clinic researchers have discovered a new immunotherapy target, a cryptic antigen, that may be key in helping the immune system fight tumors in ovarian cancer. The study, published in Science Advances, could improve treatment approaches for this ty…
What factors influence the success or failure of immunotherapy treatment in patients with advanced bladder cancer? Why do only 20% of advanced bladder cancer cases respond to immunotherapy? These are the questions addressed by a recent study led by the…
Immune therapy has transformed how cancer is treated, but many tumors continue to evade these treatments, thanks to their resemblance to healthy tissue. Now, researchers at UC San Francisco have found that some cancers, like deadly brain cancer (glioma…
University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood—known as the tertiary lymphoid structure—where they be…
