The tissue adjacent to a tumor behaves differently than areas farther away. The tumor’s cancerous cells influence their surroundings, blocking the body’s immune defenses and creating a sort of haven in which the tumor can grow. Treatments that target s…
Bowel cancer is the fourth most common cancer in the UK, and the second most common cause of cancer death. The disease falls into two types: one where proteins that repair errors in DNA are missing or deficient (the deficient subtype), and one where th…
Cancer therapies do not always succeed in eliminating tumor cells. Some of these cells enter a state of senescence—a latent, non-dividing state that is generally irreversible. Others, however, enter a state known as “persistence,” where dormancy is tem…
A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell clusters called tertiary lymphoid structures (TLSs) in response to foreign threats such as cancer.
A new paper by a team of Concordia researchers from the departments of Biology and Physics proposes a novel method of fighting cancer tumors that uses ultrasound-guided microbubbles—a technology already widely used in medical imaging and drug delivery.
A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine…
A new type of cell-based immunotherapy shows promise for B-cell lymphomas, and due to innovations in manufacturing, could make future cellular immunotherapies less expensive and more accessible to patients.
Immunotherapy is a modern approach to cancer treatment that uses a patient’s own immune system to help fight tumors. It has made an incredible impact on treating cancers in many different organ systems, including the lung, kidney, and bladder—but for o…
Preclinical research findings from the University of North Carolina Lineberger Comprehensive Cancer Center have identified a cocktail of three different drugs that can be used to generate more robust immune system CAR-Ts (chimeric antigen receptor-T ce…
A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor (CAR) T cells kill cancer.
