Serendipity reveals new method to fight cancer with T cells
A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently.
Oncology & Cancer
Engineered plasma cells show long-lasting antileukemic activity in mice
Researchers show for the first time that engineered human plasma B cells can be used to treat a disease—specifically leukemia—in a humanized animal model. The results mark a key step in the realization of ePCs as therapies to treat cancer, auto-immune …
Light targets cells for death and triggers immune response with laser precision
A new method of precisely targeting troublesome cells for death using light could unlock new understanding of and treatments for cancer and inflammatory diseases, University of Illinois Urbana-Champaign researchers report.
Review explores potential of senescent cell-derived vaccines for cancer and aging
A new review paper titled “Senescent cell-derived vaccines: a new concept towards an immune response against cancer and aging?” has been published in Aging.
The current state of immunotherapy in colorectal cancer
Colorectal cancer (CRC) is a major health concern worldwide, characterized by high incidence and mortality rates. Despite advances in treatment, metastatic CRC (mCRC) remains particularly challenging.
New therapy strengthens the immune system’s counterattack on skin cancer
An international research team has demonstrated a method to identify the cells in the immune system that can recognize and fight cancer cells in samples from 9 out of 10 patients affected by the rare but aggressive form of skin cancer, Merkel cell carc…
New antibody harbors great potential for fighting blood cancer
Acute lymphoblastic leukemia (ALL) is the most common cancer in children. This form of blood cancer, which also occurs in adults, is caused by malignantly degenerated precursor cells of certain white blood cells (B-cell precursors or T-cells) that divi…
Breakthrough research makes cancer-fighting viral agent more effective
When a cancer cell doesn’t respond to traditional therapies, doctors may turn to a sort of viral biological warfare, by deploying “troops” in the form of viral agents that are specifically engineered to target and eliminate cancer cells. The mode of at…
Study suggests changing the gut microbiome improves health outcomes for newly-diagnosed metastatic kidney cancer
Physician scientists from City of Hope, one of the largest cancer research and treatment organizations in the United States, found that people with metastatic kidney cancer who orally took a live biotherapeutic product called CBM588 while in treatment …
Understanding the mechanism behind melanoma resistance to treatment
In many cases of malignant melanoma, the effect of targeted treatment is lost over time. A research team from UZH and USZ has now discovered that a factor secreted by tumor cells is responsible for the resistance. These findings could pave the way for …