- A Dock8-dependent mechanosensitive central actin pool maintains T cell shape and protects the nucleus during migration
by inmunoadmin
Science Immunology, Volume 10, Issue 109, July 2025.
- Regulatory T cells in brown adipose tissue safeguard thermogenesis by restraining interferon-γ–producing lymphocytes
by inmunoadmin
Science Immunology, Volume 10, Issue 109, July 2025.
- Tissue origin and virus specificity shape human CD8+ T cell cytotoxicity
by inmunoadmin
Science Immunology, Volume 10, Issue 109, July 2025.
- OTUD3 prevents ulcerative colitis by inhibiting microbiota-mediated STING activation
by inmunoadmin
Science Immunology, Volume 10, Issue 109, July 2025.
- Interactions between placental Hofbauer cells and L. monocytogenes change throughout gestation
by inmunoadmin
Science Immunology, Volume 10, Issue 109, July 2025.
- Noncanonical Hedgehog signaling through Smoothened controls cytotoxic T cell migration in the tumor microenvironment
by inmunoadmin
Science Immunology, Volume 10, Issue 109, July 2025.
- Innate lymphoid cells originate from fetal liver–derived tissue-resident progenitors
by inmunoadmin
Science Immunology, Volume 10, Issue 109, July 2025.
- Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors
by inmunoadmin
Science Immunology, Volume 10, Issue 109, July 2025.
- TB or not TB: That depends on the antibody Fc
by Surabhi Kumar and Kevin C. O’Connor
Science Immunology, Volume 10, Issue 109, July 2025.
- Tuft cells restrain intestinal type 2 immunity through the transcription factor Spi-B
by inmunoadmin
Science Immunology, Volume 10, Issue 109, July 2025.
- The 10 commandments of immunoregulation in lymphoma
by Maria de los Reyes Capilla Guerra and Gabriel K. Griffin
Science Immunology, Volume 10, Issue 109, July 2025.
- Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
by inmunoadmin
Science Immunology, Volume 10, Issue 109, July 2025.
- Radiotherapy enhances anticancer CD8 T cell responses by cGAMP transfer through LRRC8A/C volume-regulated anion channels
by inmunoadmin
Science Immunology, Volume 10, Issue 108, June 2025.
- Riplet promotes lipid metabolism changes associated with CD8 T cell exhaustion and anti–PD-1 resistance in hepatocellular carcinoma
by inmunoadmin
Science Immunology, Volume 10, Issue 108, June 2025.
- TNF switches homeostatic efferocytosis to lytic caspase-8–dependent pyroptosis and IL-1β maturation
by inmunoadmin
Science Immunology, Volume 10, Issue 108, June 2025.
- CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity
by inmunoadmin
Science Immunology, Volume 10, Issue 108, June 2025.
- A linear ontogeny accounts for the development of naive, memory, and tumor-infiltrating regulatory T cells in mice
by inmunoadmin
Science Immunology, Volume 10, Issue 108, June 2025.
- Noncanonical functions of T follicular helper cells
by Shivangi Dave and André Ballesteros-Tato
Science Immunology, Volume 10, Issue 108, June 2025.
- PSGL-1 is a phagocytosis checkpoint that enables tumor escape from macrophage clearance
by inmunoadmin
Science Immunology, Volume 10, Issue 108, June 2025.
- Immuno-amnesia: Without B cells, T cells cannot remember
by Jonathan S. Maltzmannnn
Science Immunology, Volume 10, Issue 108, June 2025.
- Inflammatory mischief managed: How retinoic acid calms heart attacks at the (marrow) source
by Sahily Reyes-Esteves and Christopher A. Hunter
Science Immunology, Volume 10, Issue 108, June 2025.
- An Il12 mRNA-LNP adjuvant enhances mRNA vaccine–induced CD8 T cell responses
by inmunoadmin
Science Immunology, Volume 10, Issue 108, June 2025.
- Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance
by inmunoadmin
Science Immunology, Volume 10, Issue 108, June 2025.
- Inducible protein degradation reveals inflammation-dependent function of the Treg cell lineage–defining transcription factor Foxp3
by inmunoadmin
Science Immunology, Volume 10, Issue 108, June 2025.
- An activating Stat1 mutant disrupts normal STAT4 innate lymphocyte programs during viral infection
by inmunoadmin
Science Immunology, Volume 10, Issue 107, May 2025.
- Human LY9 governs CD4+ T cell IFN-γ immunity to Mycobacterium tuberculosis
by inmunoadmin
Science Immunology, Volume 10, Issue 107, May 2025.
- A light-regulated circadian timer optimizes neutrophil bactericidal activity to boost daytime immunity
by inmunoadmin
Science Immunology, Volume 10, Issue 107, May 2025.
- An engineered viral protein activates STAT5 to prevent T cell suppression
by inmunoadmin
Science Immunology, Volume 10, Issue 107, May 2025.
- ILC3s promote intestinal tuft cell hyperplasia and anthelmintic immunity through RANK signaling
by inmunoadmin
Science Immunology, Volume 10, Issue 107, May 2025.
- Cross-regulation between the nervous system and type 2 immunity
by Nicholas M. Mroz, Pailin Chiaranunt, Anna V. Molofsky, Ari B. Molofsky
Science Immunology, Volume 10, Issue 107, May 2025.
- C/EBPα activates Irf8 expression in myeloid progenitors at the +56-kb enhancer to initiate cDC1 development
by inmunoadmin
Science Immunology, Volume 10, Issue 107, May 2025.
- Uptake of lipids from ascites drives NK cell metabolic dysfunction in ovarian cancer
by inmunoadmin
Science Immunology, Volume 10, Issue 107, May 2025.
- Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ
by inmunoadmin
Science Immunology, Volume 10, Issue 107, May 2025.
- How dengue defies dogma: An extrafollicular tale
by Jordan Polster and David R. Martinez
Science Immunology, Volume 10, Issue 107, May 2025.
- Tolerance requires diversity (of antigen presenting cells)
by Danielle R. Jacobsen and Stephanie C. Eisenbarth
Science Immunology, Volume 10, Issue 107, May 2025.
- Apoptotic cells are not all created equal
by Amanda O. Wong and Kodi S. Ravichandran
Science Immunology, Volume 10, Issue 107, May 2025.
- Distinct type I and II interferon responses direct cortical and medullary thymic epithelial cell development
by inmunoadmin
Science Immunology, Volume 10, Issue 107, May 2025.
- Fibroblastic reticular cells form reactive myeloid cell niches in human lymph nodes
by inmunoadmin
Science Immunology, Volume 10, Issue 107, May 2025.
- Cell type–specific efferocytosis determines functional plasticity of alveolar macrophages
by inmunoadmin
Science Immunology, Volume 10, Issue 107, May 2025.
- Erratum for the Research Article “IL-4 induces CD22 expression to restrain the effector program of virtual memory T cells” by B. Yang et al.
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 10, Issue 106, April 2025.
- Clone tracking through repeated malaria identifies high-fidelity memory CD4 T cell responses
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- T–B cell cooperation in ectopic lymphoid follicles propagates CNS autoimmunity
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Endothelial-driven TGFβ signaling supports lung interstitial macrophage development from monocytes
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- CCR8+ decidual regulatory T cells maintain maternal-fetal immune tolerance during early pregnancy
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Erratum for the Research Article “Anti–immune complex antibodies are elicited during repeated immunization with HIV Env immunogens” by S. Brown et al.
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 10, Issue 106, April 2025.
- Psychological stress increases skin infection through the action of TGFβ to suppress immune-acting fibroblasts
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Foxo1 regulates intestinal tissue–resident memory CD8 T cell biology in an anatomic compartment– and context-specific manner
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Bcl11a maintains hematopoietic stem cell function but accelerates inflammation-driven exhaustion during aging
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- They are what they eat
by Asha Pillai
Science Immunology, Volume 10, Issue 106, April 2025.
- Luck gone cold: A trifecta of B cell mutations associates with cryoglobulinemia
by Kangzhi Chen and Kevin C. O’Connor
Science Immunology, Volume 10, Issue 106, April 2025.
- Eosinophil innate immune memory after bacterial skin infection promotes allergic lung inflammation
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Brain sensing of metabolic state regulates circulating monocytes
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Skin damage signals mediate allergic sensitization to spatially unlinked antigen
by inmunoadmin
Science Immunology, Volume 10, Issue 106, April 2025.
- Immunogenomic cancer evolution: A framework to understand cancer immunosuppression
by Shogo Kumagai, Yusaku Momoi, Hiroyoshi Nishikawa
Science Immunology, Volume 10, Issue 105, March 2025.
- An aging bone marrow exacerbates lung fibrosis by fueling profibrotic macrophage persistence
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- GM-CSF–mediated epithelial-immune cell cross-talk orchestrates pulmonary immunity to Aspergillus fumigatus
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- DNMT1 inhibition reprograms T cells to NK-like cells with potent antitumor activity
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- ATF4 drives regulatory T cell functional specification in homeostasis and obesity
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- QRICH1 mediates an intracellular checkpoint for CD8+ T cell activation via the CARD11 signalosome
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- Dynamic STING repression orchestrates immune cell development and function
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- Epidermal ZBP1 stabilizes mitochondrial Z-DNA to drive UV-induced IFN signaling in autoimmune photosensitivity
by inmunoadmin
Science Immunology, Volume 10, Issue 105, March 2025.
- Trouble at the border: An invading gut bacterium can break tolerance to self-RNA
by Rachael A. Clarknn
Science Immunology, Volume 10, Issue 105, March 2025.
- MBPeace treaty: How myelin self-peptides broker CNS tolerance
by Isabelle Leo and Etienne Caronnnn
Science Immunology, Volume 10, Issue 105, March 2025.
- Adeno-associated viral delivery of Env-specific antibodies prevents SIV rebound after discontinuing antiretroviral therapy
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- The meninges host a distinct compartment of regulatory T cells that preserves brain homeostasis
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- Altered immune landscape of cervical lymph nodes reveals Epstein-Barr virus signature in multiple sclerosis
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- LCK–co-receptor association ensures T cell lineage fidelity and maximizes epitope-specific TCR diversity
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- Linking vaccine adjuvant mechanisms of action to function
by Elana Ben-Akiva, Asheley Chapman, Tianyang Mao, Darrell J. Irvinennnnnn
Science Immunology, Volume 10, Issue 104, February 2025.
- TRAF3 is critical for initial T follicular helper cell specification via coordination of the IL-6R/IL-2R–BCL6 signaling nexus
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- Is one lymphocyte’s brake another lymphocyte’s gas?
by Thomas T. Xu and Shiv Pillainn
Science Immunology, Volume 10, Issue 104, February 2025.
- Afraid of needles? Try lotion: Engineering skin commensals for vaccination
by Daniel A. Shapiro and Christopher A. Hunternn
Science Immunology, Volume 10, Issue 104, February 2025.
- IL-4 induces CD22 expression to restrain the effector program of virtual memory T cells
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- Molecular determinants of cross-strain influenza A virus recognition by αβ T cell receptors
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- Bone marrow breakout lesions act as key sites for tumor-immune cell diversification in multiple myeloma
by inmunoadmin
Science Immunology, Volume 10, Issue 104, February 2025.
- Stem-like memory and precursors of exhausted T cells share a common progenitor defined by ID3 expression
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Trogocytosis of chimeric antigen receptors between T cells is regulated by their transmembrane domains
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Coordinated immune networks in leukemia bone marrow microenvironments distinguish response to cellular therapy
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Human naïve B cells recognize prepandemic influenza virus hemagglutinins
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Architects of immunity: How dendritic cells shape CD8+ T cell fate in cancer
by Vidit Bhandarkar, Teresa Dinter, Stefani Sprangernnn
Science Immunology, Volume 10, Issue 103, January 2025.
- Anti–immune complex antibodies are elicited during repeated immunization with HIV Env immunogens
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- TSLP acts on regulatory T cells to maintain their identity and limit allergic inflammation
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Molecular scalpels dissect new GluN1 hot spots in anti–NMDA receptor encephalitis
by Marianna Spatola and Josep Dalmaunnnnn
Science Immunology, Volume 10, Issue 103, January 2025.
- SNIPR alert! Making T cells more precise killers
by Jonathan Chuck and Laura A. Soltnnn
Science Immunology, Volume 10, Issue 103, January 2025.
- Suppression of thrombospondin-1–mediated inflammaging prolongs hematopoietic health span
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- Functional differences between rodent and human PD-1 linked to evolutionary divergence
by inmunoadmin
Science Immunology, Volume 10, Issue 103, January 2025.
- NEK7 phosphorylation amplifies NLRP3 inflammasome activation downstream of potassium efflux and gasdermin D
by Jie Xu, Lingzhi Zhang, Yanhui Duan, Fangyuan Sun, Nouha Odeh, Yuan He, Gabriel Núñeznnn
Science Immunology, Volume 10, Issue 103, January 2025.
- Erratum for the Research Article “GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing” by J. E. Heraud-Farlow et al.
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 9, Issue 102, December 2024.
- Meeting report: Hidden links in autoimmunity
by Mireia Guerau-de-Arellano, Margaret A. Morris, Matthew A. Sherman, Thomas R. Eschnn
Science Immunology, Volume 9, Issue 102, December 2024.
- NK cells restrain cytotoxic CD8+ T cells in the submandibular gland via PD-1–PD-L1
by Samantha M. Borys, Shanelle P. Reilly, Ian Magill, David Zemmour, Laurent Brossaynnnnn
Science Immunology, Volume 9, Issue 102, December 2024.
- Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells
by Seongji Park, Jeonghyun Ahn, Glen N. Barbernnn
Science Immunology, Volume 9, Issue 102, December 2024.
- Extrasinusoidal macrophages are a distinct subset of immunologically active dural macrophages
by inmunoadmin
Science Immunology, Volume 9, Issue 102, December 2024.
- Erratum for the Research Article “Acquisition of suppressive function by conventional T cells limits antitumor immunity upon Treg depletion” by S. K. Whiteside et al.
by AAAS: Science Immunology: Table of Contents
Science Immunology, Volume 9, Issue 102, December 2024.
- Crystal structure of the human LAG-3–HLA-DR1–peptide complex
by inmunoadmin
Science Immunology, Volume 9, Issue 102, December 2024.
- Asparagine availability controls germinal center B cell homeostasis
by inmunoadmin
Science Immunology, Volume 9, Issue 102, December 2024.
- Immunopathology in human tuberculosis
by Thomas J. Scriba, Mahlatse Maseeme, Carly Young, Laura Taylor, Alasdair J. Lesliennnnnn
Science Immunology, Volume 9, Issue 102, December 2024.
- It’s the little things in life: Lymph node microniches drive TH2 formation in allergic asthma
by Kelly Butler and Adam Williamsnnnn
Science Immunology, Volume 9, Issue 102, December 2024.