In 2023, researchers at Baylor College of Medicine led by the late Dr. Bert O’Malley discovered that the steroid receptor coactivator 3 (SRC-3) in immune cells called regulatory T cells (Tregs) plays a decisive role in shaping the anti-cancer immune re…
Lymph nodes are key control centers in the immune system and play an important role in defending the body against infections and tumors. For these processes to function properly, immune cells (B cells and T cells) must be organized in a precise spatial…
UT Southwestern Medical Center researchers have identified how the quintessential immune protein known as stimulator of interferon genes (STING) migrates from one cellular organelle to another, a necessary step in its activation. The findings, publishe…
Some viruses that make us sick are cleared by the immune system within days, while others lurk in our bodies for a lifetime and reemerge later to cause new problems. How and why viral levels in the body change over time—and the health impacts of these …
Living with a dog does not seem to worsen long-term asthma severity in children with allergic asthma, but may increase the risk of asthma exacerbations slightly, according to a study from Karolinska Institutet in Sweden that has been published in the J…
Consider two seemingly unrelated medical puzzles. First: Every day, our bodies produce hundreds of billions of new cells, many of which are mutated. If cancer arises from cellular mutation, why don’t we all have the disease all the time? Second: Severe…
As antibiotic resistance continues to rise worldwide, scientists are searching for new strategies to combat infections. This latest research at Trinity Translational Medicine Institute at Trinity College Dublin combats this problem by focusing on stren…
Our immune system protects the body from infections and harmful changes throughout our lives. However, it loses its effectiveness with age, resulting in an increased risk of disease. But what happens when the immune system ages—and can this process pos…
When someone gets a bad infection, the body’s immune system rushes in to fight the germs. But sometimes this defense system becomes too strong and starts hurting the person’s own tissues and organs. This condition, known as sepsis, is still one of the …
In a paradigm-breaking study, researchers have discovered a novel way the immune system, specifically T cells, attack their target cells, reshaping long-held assumptions in immunology and demonstrating direct implications for the field of cancer immuno…
