Trends in Immunology

J Immunol. 2026 Jun 7;215(6):vkag156. doi: 10.1093/jimmun/vkag156. NO ABSTRACT PMID:42300803 | DOI:10.1093/jimmun/vkag156

J Leukoc Biol. 2026 Jun 16:qiag079. doi: 10.1093/jleuko/qiag079. Online ahead of print. ABSTRACT Neutrophils, the most abundant innate immune cells, act as first responders in host defense via phagocytosis, degranulation, ROS production and Neutrophil Extracellular Traps (NETs) formation. Emerging evidence reveals that neutrophils are highly plastic and heterogeneous, acting as critical regulators in tumor biology. … Read more

Curr Opin Immunol. 2026 Jun 15;101:102802. doi: 10.1016/j.coi.2026.102802. Online ahead of print. ABSTRACT Lymphatic vessels maintain fluid balance and immune protection by transporting fluid, solutes and cells from tissue interstitial spaces to lymph nodes. The lymphatic endothelial cells that form lymphatics differentiate throughout the body to fulfil organ-specific roles. In the lungs, specialised pulmonary lymphatic … Read more

J Immunol. 2026 Jun 7;215(6):vkag116. doi: 10.1093/jimmun/vkag116. ABSTRACT Interferon-gamma (IFN-γ) is a powerful transactivating signal eliciting hundreds of IFN-stimulated genes (ISGs) in humans to help combat infection. Most ISGs remain uncharacterized, and here we searched for actin-binding candidates that could potentially target intracellular pathogens to block their spread or promote immune cell migration into infected … Read more

Trends Immunol. 2026 Jun 15:S1471-4906(26)00156-0. doi: 10.1016/j.it.2026.06.004. Online ahead of print. ABSTRACT While androgen deprivation is widely used in urological oncology to restrain tumor growth and prevent T cell exhaustion, Lee et al. reveal a striking reversal in glioblastoma. In glioblastoma, androgen loss triggers microglial cytokines, activates the hypothalamic-pituitary-adrenal axis, and induces glucocorticoid-dependent T cell … Read more