How unique immune cells can recognize and destroy tumors

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by Sarah C.P. Williams, Gladstone Institutes

Schematic of regulation of the BTN2A1–BTN3A1–BTN3A2 complex. Model of regulation of the butyrophilin complex uncovered in the context of known activity by the mevalonate pathway and NLRC5. Credit: Nature (2023). DOI: 10.1038/s41586-023-06482-x — Schematic of regulation of the BTN2A1–BTN3A1–BTN3A2 complex. Model of regulation of the butyrophilin complex uncovered in the context of known activity by the mevalonate pathway and NLRC5. Credit: *Nature* (2023). DOI: 10.1038/s41586-023-06482-x

Gamma delta T cells, a special type of cell in the immune system, are incredibly effective at recognizing and killing cancer cells. Cancer patients with higher levels of these T cells in their tumors tend to fare better than those with lower levels. But scientists have struggled to understand exactly how gamma delta T cells can recognize cancerous cells, and how new cancer therapies may be able to take advantage of these powerful immune cells.

https://medicalxpress.com/news/2023-08-unique-immune-cells-destroy-tumors.html

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