Probiotic delivers anticancer drug to the gut
Researchers shrink gastrointestinal tumors in mice using a yeast probiotic to deliver immunotherapy to the gut, offering a potentially novel strategy to target hard-to-reach gut cancers.
Immune System News -- ScienceDaily
Human immune system is ‘ready to go’ long before birth
The most comprehensive map of the developing human thymus sheds light on how immune responses are built and maintained at early life, with implications for understanding and treating immunodeficiency, autoimmunity, and cancer.
Study identifies subtypes of fibroblasts in skin cancer
A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment. The results are relevant for the development of novel skin cance…
New nasal vaccine shows promise in curbing whooping cough spread
A new nasal whooping cough vaccine showed an ability to prevent both infection and transmission of the disease in mice. Current vaccines offer treatment but fail to halt transmission of the bacteria that cause the disease.
When hepatitis E viruses attack nerve cells
Hepatitis E viruses (HEV) typically cause liver infections. They can, however, also infect other organs and cause neurological disorders. Little is yet known about how this process works. A research team has now developed a cell model to study the inte…
Drug combination prompts immune response in some resistant pancreatic cancers
A new drug strategy that regulates the tumor immune microenvironment may transform a tumor that resists immunotherapy into a susceptible one, according to a new study.
Treatment advances, predictive biomarkers stand to improve bladder cancer care
Recent advances in bladder cancer treatments may offer hope of curative care to more patients, including those with high-risk localized, muscle-invasive disease, according to a new editorial.
New therapeutic approach for severe COVID-19: Faster recovery and reduction in mortality
Researchers have tested a novel therapeutic concept to treat virus-induced lung failure in patients with severe COVID-19 in a phase 2 clinical trial. The approach may also be applicable to other infections.
Key influenza-severity risk factor found hiding in plain sight on our antibodies
Why do some people develop severe flu symptoms? A study points the finger at an unsung portion of the antibodies our immune systems generate to fend off invading pathogens.
Lab-grown human immune system uncovers weakened response in cancer patients
These miniature immune system models — known as human immune organoids — mimic the real-life environment where immune cells learn to recognize and attack harmful invaders and respond to vaccines. Not only are these organoids powerful new tools for st…