How tumors induce immune suppressor cells and evade immunotherapy
Researchers recently published a study that shines new light on a next-generation target of immunotherapy — the immune checkpoint protein VISTA.
Researchers recently published a study that shines new light on a next-generation target of immunotherapy — the immune checkpoint protein VISTA.
Researchers have discovered a previously unknown ability of a group of immune system cells, known as Atypical B cells (ABCs), to fight infectious diseases such as malaria. The scientists say ABCs could also be key to developing new treatments for chron…
A novel PET imaging technique can noninvasively detect active inflammation in the body before clinical symptoms arise, according to new research. Using a PET tracer that binds to proteins present on activated immune cells, the technique produces images…
Scientists discovered a pathway from mitochondrial DNA replication stress to immune system activation and inflammation, finding that endosomes responsible for disposing of dysfunctional mitochondrial DNA were leaking mitochondrial DNA into the cell and…
In a recent study of the brain’s waste drainage system, researchers discovered a direct connection between the brain and its tough protective covering, the dura mater. These links may allow waste fluid to leave the brain while also exposing the brain t…
Chronic stress affects the immune system and the brain. Researchers now show that a particular enzyme found in cells of the immune system enters the brain under stress. In mice, it causes them to withdraw and avoid social contact. This newly discovered…
A new study identifies numerous pathways by which the gut microbiome may change the immune system.
New research reveals as much as a four-fold increase in immune response when people alternate from one arm to the other when given a multi-dose vaccine.
An initial trial suggests that a new drug, originally developed for use with cancer patients, could improve the survival of patients with acute respiratory distress syndrome (ARDS). The patients in the trial were all critically unwell with ARDS, caused…
Researchers have worked out how to fix a defect that causes lupus, and hope their discovery will offer effective long-term treatment.