Cardiology

Some patients being treated with immune checkpoint inhibitors, a type of cancer immunotherapy, develop a dangerous form of heart inflammation called myocarditis.

If you cut your arm or undergo surgery, scarring can be a good thing; the scar tissue produced by cells called fibroblasts helps you heal. In most organs of the body, however, the accumulation of scarring (called fibrosis) is a sign of chronic disease …

A new study from Washington University School of Medicine in St. Louis suggests that a type of immunotherapy—similar to that approved by the Food and Drug Administration (FDA) to treat inflammatory conditions such as arthritis—also may be an effective …

Researchers at Karolinska Institutet have identified a new potential risk marker for cardiovascular disease in women. A new study shows an association between low levels of an anti-inflammatory antibody and the risk of heart attack and coronary heart d…

A paper, “Macrophages suppress cardiac reprogramming of fibroblasts in vivo via IFN-mediated intercellular self-stimulating circuit,” published in Protein & Cell uncovers a previously unappreciated mechanism by which macrophages influence the fate of C…

Cardiovascular disease is the leading cause of death in patients suffering from lupus, an autoimmune disease in which our immune system attacks our own tissues and organs, the heart, blood, lung, joints, brain, and skin. Lupus myocarditis—inflammation …

An unhealthy lifestyle, diseases or injuries, genetic predisposition, and increased coagulation tendency can promote the formation of thrombi in blood vessels. These clots obstruct the flow of blood to vital organs, which may lead to life-threatening i…

How a person’s immune system responds to a protein called LL-37 may increase the risk of developing acute coronary syndrome, but the response may also serve as a potential target for future treatments. These findings come from a research study led by i…

A stroke not only causes acute damage to the brain, but can also have long-term health implications for other organs—such as the heart. “However, there has been little research to date on the effects of brain injuries on systemic immunity,” says Profes…

There’s still much to learn about how doxorubicin, a 50-year-old chemotherapy drug, causes its most concerning side effects. While responsible for saving many lives, this treatment sometimes causes cardiac damage that stiffens the heart and puts a subs…