An immune system defect makes affected individuals vulnerable to severe viral diseases such as influenza or COVID-19. It is caused by the body’s own antibodies, which inhibit important defense proteins known as type I interferons. UZH researchers have …
Imagine a previously unknown bug—new to our immune defenses—that suddenly emerged and rapidly spread all over the globe, causing the deaths of millions and an economic breakdown due to the interruption of work in virtually every country.
Prior exposures to specific types of seasonal influenza viruses promote cross-reactive immunity against the H5N1 avian influenza virus, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Older adults who w…
A new Oregon Health & Science University and Weill Cornell Medicine co-authored study provides critical insight for the development of a vaccine that can more effectively block the spread of cytomegalovirus (CMV) across the placenta to babies before th…
A new study from The Hospital for Sick Children (SickKids) reveals the process underlying protein organization on cell membranes, a finding that could pave the way for innovative cystic fibrosis treatments.
University of Virginia School of Medicine scientists have discovered how severe COVID-19 can destroy immune cells’ ability to repair the lungs, helping explain the lingering effects of long COVID. The findings suggest a new treatment approach for long …
Infections with the hepatitis E virus often go unnoticed because they cause no symptoms. However, in patients with a weakened immune system or existing liver damage and also in pregnant women, the virus can cause severe liver inflammation, which can be…
Systemic lupus erythematosus, or lupus, is a complex autoimmune disease in which the immune system mistakenly attacks healthy tissue, often affecting the skin, joints, kidneys and nervous system. Lupus symptoms include inflammation, skin rashes, joint …
Researchers have uncovered changes in the cellular response throughout lung damage caused by SARS-CoV-2—the virus behind COVID-19. The team revealed distinct phases where waves of immune responses give way to lung fibrosis—scarring of the lungs—in seve…
A research team led by Prof. Zeng Zhutian from the University of Science and Technology of China (USTC) has identified and named a novel population of bladder-resident macrophages, termed suburothelial perivascular macrophages (suPVMs), which can preve…
