All cells in the body contain the same DNA, but different cell types express different genes; skin cells express genes for the skin, liver cells express liver genes, and so on. This coordination is crucial to help cells differentiate into their assigne…
Many diseases affect men and women differently. Asthma tends to strike men earlier in life, yet more women develop asthma as they get older. Parkinson’s is more common in men, but Alzheimer’s is more common in women.
Findings from St. Jude Children’s Research Hospital demonstrate that virtual memory T cells, a specialized group of immune cells, provide nonspecific immunity for infants early in life.
Brazilian researchers have taken an important step toward precision medicine by identifying four genes that can predict which melanoma patients will not respond to immunotherapy. Although this treatment has revolutionized the fight against melanoma, th…
Controlling the activity of specific genes in the laboratory through the editing of their epigenetic marks is now a reality thanks to the CRISPR technology. A team from the Josep Carreras Leukemia Research Institute has demonstrated that it is possible…
Doctors and genetic researchers at The University of Manchester have discovered that changes in a gene leads to severe nerve damage in children following a mild bout of infection.
In a newly published article in Nature Genetics, researchers from the University of Chicago have identified tumor aneuploidy—an imbalance in the number of chromosomes—as a powerful biomarker associated with resistance to immunotherapy across cancer typ…
At the start of the COVID-19 pandemic, information began to trickle in about who was at higher risk of a dangerous outcome from infection: men, those over 65, smokers, those with obesity. It turns out these seemingly unrelated categories of people have…
Why do people develop antibodies to food? While clinicians have long observed that healthy humans develop a particular type of antibody, called IgG, to the foods they eat, the reasons for this phenomenon have remained unknown.
Using a modern imaging technology known as cryo-electron microscopy, researchers at UT Southwestern Medical Center have determined the structure of a protein called midnolin that’s crucial to the survival of malignant cells in some leukemias, lymphomas…
