In a recent online publication in Science China Life Sciences, researchers from the laboratory of Leng-Siew Yeap at the Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine published a review article entitled “Molecular Me…
The immune system is tightly regulated to ensure that it only responds to actual health threats, instead of attacking our own bodies, which happens in cases of autoimmunity. Now, researchers from Japan report a new protein–protein interaction that coul…
An international team of scientists including researchers from The Australian National University (ANU) have identified a rare, mutated version of a protein called TNIP1 that causes a chronic autoimmune disease similar to Sjogren’s Syndrome—a condition…
Researchers at the Leibniz Institute for Immunotherapy (LIT) describe a new type of regulation of immune cells by so-called “jumping genes.”
Chromosome 18q deletion (18q del) syndrome is a rare genetic disorder, affecting approximately 1 in 40,000 to 55,000 individuals, caused by the deletion of genetic material on the long arm of chromosome 18. This genetic anomaly disrupts normal growth a…
Adeno-associated virus (AAV)-based viral vectors used in human gene therapy can trigger innate immune pathways, leading to the initiation of adaptive immune responses. A new review article published in the journal Human Gene Therapy describes the range…
An article published by Technion researchers in Nature presents new insights about the evolution of the immune system. The team’s findings highlight the modularity and flexibility of the evolution of immunity.
The largest genetic analysis of an autoimmune disorder known as systemic sclerosis ever conducted in an Asian population has uncovered six new DNA markers for this rare tissue disease—a discovery that promises to improve treatment for patients worldwid…
Researchers from Japan have uncovered the genetic diversity and regional patterns of CARD9 deficiency in patients susceptible to fungal diseases.
Australian and Chinese researchers have jointly discovered a genetic key to the development of the devastating autoimmune condition childhood lupus.
