Gut microbiota may be the key factor explaining why certain individuals do not respond well to the pneumococcal vaccine, a bacterium that can cause various diseases, such as pneumonia. This conclusion is drawn from a recent study led by the B Cell Biol…
In a recent study published in Science Advances, researchers led by Prof. Li Xinjian from the Institute of Biophysics of the Chinese Academy of Sciences have uncovered a novel immunoregulatory function of isocyanic acid (ICA), a reactive metabolite syn…
Not long after a threatening organism enters our bodies, our immune system springs into action and starts producing proteins known as type one interferons (IFN-I), which fight viruses and cancer, while also playing pathogenic roles in autoimmune disord…
What if treating autoimmune diseases was as simple as regulating the acidity levels of parts of patients’ cells? Genetic screening may have unlocked a path for treating the severe inflammation associated with many immune diseases by regulating one prot…
Vaccine effectiveness relies on creating a strong antibody response that can be reactivated to fight future infections. Now, researchers from Japan report that antibody-producing cells are destined for longevity from the moment they are born.
A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce new blood cells, according to a preclinical study led by Weill Cornell Medicine investigators. The discovery could lead to more …
New research suggests that receiving multiple doses of a vaccine in the same limb leads to faster antibody development, an important strategy for providing immunity as quickly as possible during a pandemic or disease outbreak.
Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and their collaborators demonstrated a remarkable ability t…
New research from RCSI University of Medicine and Health Sciences has found that white blood cells which ‘remember’ past inflammatory events are quick to overreact, raising the risk of blood clots.
Preterm babies are fragile. This is especially true for infants born just six to seven months into a pregnancy. Called extremely preterm infants, these children essentially finish developing outside the uterus. Studying this vulnerable population is ch…
