Injectable drug helps asthma patients clear mucus-clogged airways
An anti-inflammation injectable drug can reduce mucus buildup and improve breathing among asthma patients, a new clinical trial says.
Immunology
Bisphenol A causes sex-specific changes in metabolism and the immune system, study reveals
Even small amounts of bisphenol A can lead to long-term health effects. When researchers studied adult rats exposed in the fetal stage, they found that females had developed a more masculine and males a more feminine gene expression pattern. This led t…
Mitochondria and lysosomes reprogram immune cells that dampen inflammation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children’s Research Hospital scientists recently uncovered how mitochondria, the powerhouse of cells, a…
Psoriasis-linked gene mutation also impacts gut health, scientists discover
A mutation previously linked to skin disorders like psoriasis may also play a surprising role in gut health, according to new research published by scientists at VIB-UGent and colleagues from UGent, the University of Barcelona, and University College L…
Decades-old asthma theory challenged: Newly discovered molecules may be real drivers of disease
For decades, scientists have thought they understood the biochemical machinery that causes asthma—inflammation in the lungs that constricts airways and makes it hard to breathe.
New genomic test could spare some people with melanoma from lymph node biopsy surgery
A genomic test co-developed by Mayo Clinic and SkylineDx can identify whether people with melanoma are at low or high risk for cancer in their lymph nodes—a finding that could guide treatment decisions and help many people avoid lymph node biopsy surge…
Rethinking how bone marrow works with a unified framework
One huge reason why the world of medicine hasn’t yet found “the cure” for hard-to-treat malignancies like acute myeloid leukemia (AML) and many other forms of cancer is that the world of science is still striving to fully understand how our bone marrow…
Abnormal cell ‘conversations’ drive chronic lung-transplant rejection, research reveals
More than 50% of lung-transplant recipients experience a rejection of their new lung within five years of receiving it, yet the reason why this is such a prevalent complication has remained a medical mystery.
Less than half of schoolkids at risk of food anaphylaxis in England prescribed adrenaline ‘antidote’
Less than half of schoolchildren in England who are at risk of a serious and potentially life-threatening allergic reaction (anaphylaxis) to food were prescribed the antidote—an adrenaline [epinephrine] autoinjector, or AAI for short—finds an analysis …
Recurrence-free survival longer with nivolumab than ipilimumab in melanoma: Study
For patients with resected stage IIIB-C or stage IV melanoma, recurrence-free survival is longer with nivolumab than ipilimumab, according to a study published online Oct. 18 in the New England Journal of Medicine to coincide with the annual meeting of…