Daylight can boost the immune system’s ability to fight infections
A breakthrough study, led by scientists at Waipapa Taumata Rau, University of Auckland, has uncovered how daylight can boost the immune system’s ability to fight infections.
Immunology
Organ-specific inflammation masquerades as relapse in CAR T-cell remission
Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have identified a previously undocumented, organ-specific toxicity linked to CD19-targeted CAR T-cell therapy in autoimmune disease. The syndrome, termed local immune effector cell-associ…
Stem cell transplant offers potentially curative therapy in pediatric patients with monogenic inflammatory bowel disease
A collaborative team of researchers from Children’s Hospital of Philadelphia (CHOP) found that hematopoietic stem cell transplantation (HSCT) is a highly effective method for treating patients with monogenic inflammatory bowel disease (IBD), a more sev…
Aging reduces CAR-T cell effectiveness by impairing metabolism, study shows
As people age, their immune systems become less efficient, posing a challenge for cancer therapies that rely on harnessing immune cells.
Streamlined technique rapidly measures cells’ density, reflecting health and developmental state
Measuring the density of a cell can reveal a great deal about the cell’s state. As cells proliferate, differentiate, or undergo cell death, they may gain or lose water and other molecules, which is revealed by changes in density.
Inhaled microplastics inhibit key immune cell in the lungs, study finds
Microplastics are ubiquitous in the environment, and we all routinely inhale these tiny pollutants. Now, new research published at the ATS 2025 International Conference has found that inhaled microplastics suppress pulmonary macrophages, a type of whit…
Positive proof-of-concept experiments may lead to the world’s first treatment for celiac disease
An investigational treatment for celiac disease effectively controls the condition—at least in an animal model—in a first-of-its-kind therapeutic for a condition that affects approximately 70 million people worldwide.
Study shows infant immune systems respond differently to severe COVID-19
Infants hospitalized with severe COVID-19 have significantly different immune responses than adults or older children. The finding comes from scientists at St. Jude Children’s Research Hospital, The Jackson Laboratory for Genomic Medicine, Weill Cornel…
New B meningococcus vaccine shows promise in early-stage trial
The outcome of a trial published in Science Translational Medicine, shows encouraging results for a new vaccine targeting group B meningococcus (MenB), a significant cause of meningococcal disease worldwide, and establishes proof-of-concept in humans t…
Betrayed by bile ducts? Researchers look for clues to treating a mysterious autoimmune disease
Your bile duct network is a true tree of life. A floppy, pink tree of life.