Researchers reveal how psychological stress may aggravate skin allergies
Psychological stress is known to exacerbate skin allergies, but the underlying molecular mechanisms remain poorly understood.
Immunology
Exploring IL-8⁺ neutrophils and their role in severe alcohol-associated hepatitis
Alcohol-associated hepatitis (AH) is a critical global health issue characterized by acute liver inflammation and an elevated risk of mortality in its severe form (sAH). While the condition has been studied extensively, effective treatments remain scar…
Scientists develop ‘suspended animation’ technique for blood draws to aid research for underserved populations
Your blood is a delicate mixture. Researchers and clinicians often use blood to learn what’s going on inside our bodies, in part because siphoning off a tube of blood is easier and less painful than taking biopsies of an internal organ.
How a simple amino acid could shape immune response
A study conducted by researchers at the Kennedy Institute of Rheumatology has uncovered a pivotal role of asparagine metabolism in regulating B cell homeostasis and immune response.
Targeting tristetraprolin in basophils: Researchers find promising therapeutic target for allergic inflammation
Inflammation is a crucial part of the body’s defense mechanism, playing a key role in fighting infections and repairing tissue damage. Basophils, a type of immune cell that makes up less than 1% of white blood cells, have recently emerged as critical p…
Blood test can predict how long vaccine immunity will last, study shows
When children receive their second measles-mumps-rubella vaccine, around the time they start kindergarten, they gain protection against all three viruses for all or most of their lives. Yet the effectiveness of an influenza vaccine given in October sta…
Scientists link hematopoietic cell transplant deaths to beta-blocker use
Patients can die if they take certain previously prescribed beta-blockers during a hematopoietic cell transplant due to suppressed signals from nerves that promote bone marrow regeneration.
Unclogging the immune system: Scientists use immunotherapy to remove aging cell buildup
Whenever a sink overflows, the flooding is usually caused by a blockage that has built up in the drains. Similarly, as we age, our bodies are flooded by aging, or senescent cells, which have stopped dividing but, instead of dying, remain active and bui…
Loosening chimeric antigen receptor’s grip on T-regulatory cells improves function, researchers find
A new paper from MUSC Hollings Cancer Center researchers is helping to reveal the “rules” for engineering chimeric antigen receptor (CAR) Tregs.
Study links alcohol consumption to more severe nut allergy reaction
Findings of a new study into severe allergic reactions offer a sobering warning to people allergic to tree nuts and, more broadly, could lead to quicker diagnoses in emergency care for people with all anaphylactic allergies.