A new study published in the Proceedings of the National Academy of Sciences suggests that rare cases of brain inflammation linked to live-attenuated yellow fever and Chikungunya vaccines were due to autoantibodies carried in a small subset of the popu…
As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines are less effective. New research carried out by Dr. Loren Kell at NDORMS shows that immune cells in older people have damaged DNA…
Allergic diseases represent a major global health burden, placing significant strain on health care systems worldwide. Severe conditions such as anaphylaxis, asthma, food allergy, and allergic rhinitis are driven by immunoglobulin E (IgE), an antibody …
Atopic dermatitis (AD) is a chronic disease that affects an increasing number of children and adults. The skin is dry and irritated, and the itching can be so severe that it interferes with sleep and daily life. Although AD has been discussed for years…
Researchers from Universidad Carlos III de Madrid (UC3M), the National Center for Cardiovascular Research (CNIC), and Yale University (U.S.) have published a comprehensive review article in the journal Cell that proposes a new framework for understandi…
How do immune cells strike a balance, unleashing rapid attacks against pathogens or cancer, while avoiding damage to healthy cells? Research into an immune kill switch holds potential for controlling infections or preventing autoimmunity.
A new comprehensive review from researchers at the Icahn School of Medicine at Mount Sinai details how decades of cancer vaccine research are converging into a new era of more precise, personalized, and effective immunotherapies, particularly when comb…
Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment involves CD8⁺ T cells, also known as killer T cells, which play a crucial role in attacking tumors. Unfortunately, these cells grad…
In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the “recipe” for the transformation. Researchers at Lund University have now created a library of the 400 factors needed for reprogrammi…
Abdominal fat is not a uniform tissue. A new study from Karolinska Institutet, Steno Diabetes Center Copenhagen, and Helmholtz Munich reveals that fat located close to the large intestine contains an unusually high number of inflammatory fat cells and …
