Immune checkpoint inhibitors (ICIs) are a class of immunotherapy that have revolutionized the treatment of cancer. However, they can cause a wide variety of autoimmune toxicities, including immune checkpoint inhibitor-associated acute kidney injury (IC…
Why do some people feel itchy after a mosquito bite or exposure to an allergen like dust or pollen, while others do not? A new study has pinpointed the reason for these differences, finding the pathway by which immune and nerve cells interact and lead …
Scientists from the Karolinska Institutet in Sweden and Imperial College London have shown for the first time which aspects of our immune systems are regulated by sex hormones, and the impacts this has on disease risk and health outcomes in males and f…
A study in Frontiers of Medicine uncovers a unique reparative function of regulatory T cells (Tregs) in the process of fracture healing, a discovery that adds a new dimension to our understanding of the immune response in tissue regeneration.
A study published in Protein & Cell details experiments conducted to understand the role of IL-24 in atopic dermatitis (AD)-like conditions.
In a study that reshapes what we know about COVID-19 and its most perplexing symptoms, scientists have discovered that the blood coagulation protein fibrin causes the unusual clotting and inflammation that have become hallmarks of the disease, while al…
As researchers estimate that nearly all Americans have been exposed to SARS-CoV-2, the virus that causes COVID-19, whether through infection or vaccination, we are no longer “immunologically naive”—in other words, our immune systems are familiar with c…
Fibrotic hypersensitivity pneumonitis is a chronic and progressive interstitial lung disease, caused by an immune response to inhaled foreign antigens or allergens. Researchers from Yale’s Section of Pulmonary, Critical Care and Sleep Medicine have use…
Synthetic immunology, an innovative field of research that could lead to fundamentally new approaches and methods in the treatment of infectious diseases and cancer, is the topic of a new article published in Nature Nanotechnology.
A Ludwig Cancer Research study has identified a metabolic switch in the immune system’s T cells that is essential to the generation of memory T cells—which confer lasting immunity to previously encountered pathogens—and a T cell subtype found in tumors…
