Scientists at La Jolla Institute for Immunology (LJI) have published the first-ever, in-depth analysis of immune cell memory in the upper airways of adult volunteers. Among these immune cells, the researchers spotted “tissue resident” memory cells, whi…
Australian children with potentially deadly peanut allergies will be offered life-saving treatment in a nationwide program touted as a world first.
A study has found that a subset of a special type of white blood cells called monocytes could be the key to regrowing blood vessels in the legs of patients with chronic limb-threatening limb ischemia (CLTI).
Infecting volunteers with malaria reveals why some get sick and others don’t—and points to ways to induce stronger immunity through vaccination.
Allogeneic hematopoietic cell transplantation (HCT) is a commonly used curative therapy for individuals with inborn errors of immunity (IEI). HCT involves introducing stem cells from a compatible donor with the aim of replacing the affected cells in th…
Aging significantly impacts the immune system, notably through the involution of the thymus, which reduces T cell production. This decline weakens immune responses, making older adults more susceptible to infections and diseases. Aged T cells also exhi…
Small, laboratory-grown balls of cells made from the intestinal tissue of people with celiac disease have revealed a previously unknown molecular link between gluten exposure and intestinal damage, according to a study by researchers at Stanford Medicine.
Cornell researchers have identified a switch that regulates inflammation caused by an immune response, a finding that could one day help clinicians control inflammation-related conditions such as autoimmune, cardiovascular and neurodegenerative diseases.
Monoclonal antibodies have become indispensable in medicine to combat cancers, infectious diseases and autoimmune disorders. But the mechanism of action of a major monoclonal antibody developed for ulcerative colitis has remained elusive—until now.
A new combined cell therapy for kidney transplants can help to reduce the donor-specific reaction against the transplanted organ without the need for maintenance triple immunosuppression. The overall diversity of the T-cell receptor repertoire, which i…
