New insights on celery allergies and associated risks
Celery, a major cause of vegetable allergies, carries the risk of causing severe allergic reactions, especially in individuals with mugwort pollen sensitization.
Immunology
Study sheds light on the origin of eosinophils and effects of current precision therapies
Eosinophils are specialized cells of our immune system. They are identified by their distinctive granules that stain red when treated with an acidic reagent, eosin, that gave them their name. Eosinophils are typically rare in our blood and tissues, acc…
Researchers determine mechanism of action of delta inulin, uncover key to more effective vaccines
Researchers from the Centenary Institute and the University of Sydney have made a major discovery in vaccine science, gaining new insights into delta inulin as a crucial vaccine component. Their findings offer a promising pathway for advancing the next…
Study reveals how extremely rare immune cells predict how well treatments work for recurrent hives
A study which examines the common skin condition, chronic spontaneous urticaria (CSU), characterized by recurrent hives, has been recently published by Trinity College Dublin researchers in the journal Allergy.
Study finds tyrosine kinase Csk promotes germinal center B cell survival and affinity maturation
The immune system strikes a fine balance by identifying and neutralizing disease-causing agents while carefully avoiding destruction of healthy tissues and cells. Now, researchers from Japan have shed new light on one of the processes that helps train …
Research shows linked biological pathways driving skin inflammation
A certain biological pathway—a set of linked reactions in the body—drives the inflammation seen in the skin disease psoriasis, a new study finds. The work could lead to improved therapies for all inflammatory skin diseases, including atopic and allergi…
Genetically engineered pig hearts transplanted in two brain-dead patients reveal more about immune response
A large team of biomedical researchers affiliated with a host of institutions across the U.S., the U.K., Saudi Arabia and France, has learned more about many of the factors involved in xenotransplantation as they conducted a large number of tests on tw…
Unlocking the body’s defenses: Understanding immunotherapy
In the battle against diseases, the human body boasts an intricate defense network capable of identifying and neutralizing threats—the immune system. It serves as a guardian, constantly patrolling the body to keep it safe from invaders like bacteria, v…
Repeat COVID-19 vaccinations elicit antibodies that neutralize variants, other viruses
The COVID-19 pandemic is over, but the virus that caused it is still here, sending thousands of people to the hospital each week and spinning off new variants with depressing regularity. The virus’s exceptional ability to change and evade immune defens…
Cell types and molecules usually associated with autoimmune diseases found to be normal components of gut immunity
Researchers in the Peter Gorer Department of Immunobiology have identified that features of the immune system that were previously considered to be characteristics of autoimmune diseases are normal components of the immune system in human gut that inte…