Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque’s team at the Montreal Clinical Research Institute (IRCM) and the Maisonneuve-Rosemont Hospital Research Center have shed new light on the mechanisms governing an e…
Mucormycosis, a fungal infection caused by Mucorales, has high mortality rates in people with weakened immune systems and those suffering from severe trauma like burns, blast injuries or victims of natural disasters. The disease caused serious infectio…
Our blood consists of many cell types that develop through different stages from a precursor type—the blood stem cell. An international research team led by Universitätsmedizin Frankfurt and Goethe University has now investigated the developmental path…
An international group of researchers has identified an important mechanism that enables stem cells to evade immune rejection. Their research, published in Nature, sheds light on how these specialized cells create an “immune-privileged” environment—are…
A recent study carried out by a research team from the Paul-Ehrlich-Institut investigated the immunomodulating properties of β-glucans. These are natural sugar compounds found in bacteria, fungi and grains. The results indicate that β-glucans can targe…
Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a standard therapy for patients with acute myeloid leukemia (AML) who have relapsed after allogenic hematopoietic stem cell transpl…
Researchers at National Jewish Health and colleagues have completed the first study comparing lung macrophages in multiple models of lung injury. The research indicates that macrophages previously described as “pro-fibrotic” are insufficient to cause f…
Structural Genomics Consortium researchers at The Neuro (Montreal Neurological Institute-Hospital) of McGill University, in collaboration with scientists from 11 major antibody manufacturers representing approximately 80% of global renewable antibody p…
Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, or TLRs for short. But what signals activate TLRs, and what is the relationship between the scale and nature of this activatio…
Viruses are masters of stealth. From the moment a virus enters the host’s body, it begins hijacking its cells. First, the virus binds to a specific protein on the cell’s surface through a lock-and-key mechanism. This protein, known as a receptor, facil…
