Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system’s natural defenses against cancer. This pathway, which plays a key role in helping the body defend against potential pathogens, ca…
The innate immune system is the body’s first line of defense against pathogens and foreign substances. An essential component of this system are pattern recognition receptors, which recognize non-self RNA—such as that from viruses and bacteria—and trig…
Some cancers and chronic inflammatory diseases are treated with immunotherapies. These stimulate the patient’s immune system to recognize and destroy tumor cells. To improve such therapies, researchers are looking for mechanisms involved in triggering …
Pinpointing the precise culprits behind harmful biological processes—such as excessive scarring (fibrosis) in organs like the kidneys and lungs—has long remained challenging even though this affects almost a billion people worldwide. But thanks to the …
Scientists in Uruguay have found genotypes of the human papillomavirus (HPV) linked to cervical cancer in urban wastewater, saying it could help inform disease prevention efforts.
A common and unsightly skin cancer that can turn deadly has been undetectable for more than a year in a patient treated with a new targeted immune-therapy in a clinical trial at HonorHealth Research Institute.
Scientists at the Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) in Jena have discovered a previously unknown function of immune cells in the bone marrow.
The restricted mean survival time (RMST) analysis technique was introduced in health care research about 25 years ago and since then has become widely used in economics, engineering, business and other professions.
Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque’s team at the Montreal Clinical Research Institute (IRCM) and the Maisonneuve-Rosemont Hospital Research Center have shed new light on the mechanisms governing an e…
Mucormycosis, a fungal infection caused by Mucorales, has high mortality rates in people with weakened immune systems and those suffering from severe trauma like burns, blast injuries or victims of natural disasters. The disease caused serious infectio…
