Glucose helps T cells build cancer-fighting structures, not just provide energy
For cancer- and infection-fighting T cells, glucose offers far more than a simple sugar rush.
Medical research
Cellular therapy developed for cancer now being tested in autoimmune disease
Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, has joined with 40 other centers in the U.S. and Europe as a site in one of the first clinical trials testing cellular therapy for autoimmune disease in t…
Study reveals how immune cells transform to aid tissue healing after injury
Regulatory T cells (Treg cells) are a specialized subgroup of immune cells that play a central role in the human immune system. These cells can suppress erroneous and therefore harmful immune reactions that can lead to autoimmune diseases, for example….
T-bet protein found essential for maintaining flu-fighting memory B cells
At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody against the virus. Antigen in, antibody out.
ISS researcher links bone loss in astronauts to stem cell changes in microgravity
Mayo Clinic physician and researcher Dr. Abba Zubair’s work combines two passions—medicine and space—for the benefit of astronauts and people on Earth. His research in space is yielding discoveries in cancer, stroke, bone loss and more.
Researchers reveal key differences in STING inhibition between humans and mice
Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system’s natural defenses against cancer. This pathway, which plays a key role in helping the body defend against potential pathogens, ca…
How modified RNA tricks the innate immune system
The innate immune system is the body’s first line of defense against pathogens and foreign substances. An essential component of this system are pattern recognition receptors, which recognize non-self RNA—such as that from viruses and bacteria—and trig…
Researchers establish direct link between centromeres and immunity for the first time
Some cancers and chronic inflammatory diseases are treated with immunotherapies. These stimulate the patient’s immune system to recognize and destroy tumor cells. To improve such therapies, researchers are looking for mechanisms involved in triggering …
A ‘handbook’ to fast-track breakthroughs in scarring research
Pinpointing the precise culprits behind harmful biological processes—such as excessive scarring (fibrosis) in organs like the kidneys and lungs—has long remained challenging even though this affects almost a billion people worldwide. But thanks to the …
Wastewater helps monitor cancer-causing HPV
Scientists in Uruguay have found genotypes of the human papillomavirus (HPV) linked to cervical cancer in urban wastewater, saying it could help inform disease prevention efforts.