Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a standard therapy for patients with acute myeloid leukemia (AML) who have relapsed after allogenic hematopoietic stem cell transpl…
Researchers at National Jewish Health and colleagues have completed the first study comparing lung macrophages in multiple models of lung injury. The research indicates that macrophages previously described as “pro-fibrotic” are insufficient to cause f…
Structural Genomics Consortium researchers at The Neuro (Montreal Neurological Institute-Hospital) of McGill University, in collaboration with scientists from 11 major antibody manufacturers representing approximately 80% of global renewable antibody p…
Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, or TLRs for short. But what signals activate TLRs, and what is the relationship between the scale and nature of this activatio…
Viruses are masters of stealth. From the moment a virus enters the host’s body, it begins hijacking its cells. First, the virus binds to a specific protein on the cell’s surface through a lock-and-key mechanism. This protein, known as a receptor, facil…
Investigators are constantly aiming to identify new therapeutic approaches for regenerative medicine. Recent strategies have focused on harnessing the power of the body’s own tissue healing and repair mechanisms, including anti-inflammatory signaling m…
Researchers at Rutgers University in New Jersey have discovered that a protein produced by parasitic worms in the gut enhances wound healing in mice. The study, appearing in the journal Life Science Alliance, reveals that applying the protein to skin w…
A new review was published as the cover paper of Aging, titled “Types of cell death and their relations to host immunological pathways.”
Some people who develop a weird and terrifying allergy to red meat after a bite from a lone star tick can still eat pork from a surprising source: Genetically modified pigs created for organ transplant research.
Thin lips are not only a common cosmetic concern in patients with scleroderma, a condition that involves tightening and hardening of the skin among other effects on internal organs, but also can impact a person’s ability to chew, swallow, and sleep.
