Cell death types and their relations to host immune pathways
A new review was published as the cover paper of Aging, titled “Types of cell death and their relations to host immunological pathways.”
Medical research
Pig transplant research yields a surprise: Bacon safe for some people allergic to red meat
Some people who develop a weird and terrifying allergy to red meat after a bite from a lone star tick can still eat pork from a surprising source: Genetically modified pigs created for organ transplant research.
Hyaluronic acid lip fillers safe for patients with systemic sclerosis, study finds
Thin lips are not only a common cosmetic concern in patients with scleroderma, a condition that involves tightening and hardening of the skin among other effects on internal organs, but also can impact a person’s ability to chew, swallow, and sleep.
Chemical conjugation mitigates immunotoxicity of chemotherapy of lipid nanoparticles
While chemotherapy can stimulate antitumor immunity, it may also impair immune cell function and induce lymphodepletion, reducing the effectiveness of subsequent immunotherapy. Thus, nanoparticle-based drug delivery systems have been developed for thei…
A new method to study immune cells offers hope for finding new disease treatments
Macrophages play a critical role in the immune system by fighting infections and aiding in tissue repair. Understanding how these cells are activated in different scenarios is important for developing new medical treatments. However, identifying and st…
Circadian rhythm drives the release of important immune cells, study reveals
The sites where our bodies come into contact with the outside world—via skin, the surface of the eye, inside the mouth, the lining of the intestine and the urinary tract, for example—are known as barrier tissues.
Scientists solve decades long mystery of NLRC5 sensor function in cell death
The innate immune system is responsible for protecting the human body from threats that could cause disease or infection. The system relies on innate immune sensors to detect and transmit signals about these threats. One of the key innate immune strate…
Scientists engineer human antibodies that could neutralize black widow toxin
There are various types of widow spiders, including black, red, and brown varieties in North and South America, the Australian redback spider, and several button spider species that inhabit South Africa. In Europe, Latrodectus tredecimguttatus—the Euro…
Researchers identify key differences in inner workings of immune cells
Cytotoxic T cells are an important component of the immune system. Once activated, they differentiate into either short-lived effector cells or long-lived memory cells. Studies by researchers at ETH Zurich have found that the cellular architecture of T…
Allergy or infection? Scientists discover what distinguishes these two immune system responses
The production of antibodies, essential for protecting our body against infections, is very well regulated through the action of a specific subtype of immune system cells, follicular helper lymphocytes. Now, a team led by Luís Graça, group leader at th…