A new study has uncovered an unexpected way cancer cells can escape the immune system, making it harder for treatments to work. The study explains how a type of cancer cell death can actually make tumors grow faster by turning off the immune system’s a…
Researchers discover how mitochondria not only produce energy but also influence inflammation.
A multinational collaboration has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint inhibitors experience increased susceptibility to common infections.
Researchers recently collaborated on a novel, highly specific strategy to treat type 1 diabetes (T1D) using a tagged beta cell transplant in tandem with localized immune protection provided by specialized immune cells also tagged with a complementary b…
Researchers have analyzed the entire mouse intestine, mapping gene expression and cell states and location in the healthy gut and in response to perturbations such as inflammation. They identified tight regulation of cell types and states in different …
Hidradenitis suppurativa (HS) is an immune disease that affects up to 4% of the global population and causes painful, recurring skin lesions and inflammation, primarily in the folds of the skin. It commonly affects women of African American descent.
A new study analyzed data from participants who have been followed for over 50 years, starting before their births. Researchers found that maternal immune activity during a critical period of sex-dependent brain development in pregnancy affected the of…
Scientists have discovered how long-term treatment of high blood pressure with commonly prescribed drugs can destroy the kidney’s ability to filter and purify blood. The finding could open the door to better ways to manage high blood pressure and other…
A new study shows stimulating the vagus nerve in mice with colitis reduced stress-driven symptoms of inflammatory bowel disease by regulating SUMOylation, an immune response that triggers gut inflammation.
Researchers shrink gastrointestinal tumors in mice using a yeast probiotic to deliver immunotherapy to the gut, offering a potentially novel strategy to target hard-to-reach gut cancers.
