Immunotherapy for gum disease? Study in mice shows promise
Targeting the immune system could prevent or treat periodontal disease (PD), a common but serious disease of the gums, according to new research.
Targeting the immune system could prevent or treat periodontal disease (PD), a common but serious disease of the gums, according to new research.
Researchers found that natural immunity from previous flu infections has a significant impact on how well future influenza vaccinations work.
Lipid mediators (LMs), which are physiologically active lipids, play a critical role in promoting and suppressing acute inflammation. This study elucidates the molecular mechanisms by which macrophages, responsible for LM production, transition LMs fro…
Researchers have discovered a new bacterium that weakens the immune system in the gut, potentially contributing to certain inflammatory and infectious gut diseases. The team identified the bacterium, Tomasiella immunophila (T. immunophila), which plays…
Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study. The findings suggest a potential strategy for enhancing the pote…
Glioblastoma is the most common and most aggressive primary brain tumor, with an average survival after diagnosis of less than two years, and against which current treatments remain ineffective. In recent years, immunotherapies have given patients rene…
Results from a preclinical study in mice and a collaborative clinical study in patients show that the type 2 immune response — associated with parasitic infection and thought to play a negative role in cancer immunity — is positively correlated with …
Researchers have tested a combination of treatments in mice with lung cancer and shown that these allow immunotherapies to target non-responsive tumors.
Researchers have discovered that food antigens like milk proteins help keep tumors from growing in our guts, specifically the small intestines. Experiments revealed how these proteins trigger the intestinal immune system, allowing it to effectively sto…