A research collaboration has published a comprehensive overview of how our immune system reshapes tumor architecture in response to immune checkpoint therapy. The eight-year study outlines how cancer immunotherapy induces tumor recognition through neoa…
Scientists have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19.
A therapy showing promise to help control tuberculosis does not interfere with combined antiretroviral therapy (cART), according to new research.
New findings on how past viral respiratory infections affect future, unrelated ones could lead to therapies for boosting general antiviral immunity — and potentially pandemic preparedness.
Targeting the immune system could prevent or treat periodontal disease (PD), a common but serious disease of the gums, according to new research.
Researchers found that natural immunity from previous flu infections has a significant impact on how well future influenza vaccinations work.
Lipid mediators (LMs), which are physiologically active lipids, play a critical role in promoting and suppressing acute inflammation. This study elucidates the molecular mechanisms by which macrophages, responsible for LM production, transition LMs fro…
Researchers have discovered a new bacterium that weakens the immune system in the gut, potentially contributing to certain inflammatory and infectious gut diseases. The team identified the bacterium, Tomasiella immunophila (T. immunophila), which plays…
Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study. The findings suggest a potential strategy for enhancing the pote…
Glioblastoma is the most common and most aggressive primary brain tumor, with an average survival after diagnosis of less than two years, and against which current treatments remain ineffective. In recent years, immunotherapies have given patients rene…
