In depth analysis explains why preschoolers are less likely to develop severe COVID-19
Five years ago, at the outset of the coronavirus pandemic, a phenomenon became abundantly clear: Preschool-age children rarely developed severe cases of COVID-19.
Medical Xpress
New way to kill cancer cells could lead to longer lasting protection for people with breast cancer
Killing breast cancer cells in a way that trains the immune system to recognize and destroy residual cancer cells could offer longer lasting protection to people with the disease.
Inside RSV: Researchers pinpoint markers of more severe cases
Respiratory syncytial virus (RSV) remains the top cause of hospitalization among young children, leading to respiratory issues like bronchiolitis and pneumonia. However, the reasons why some children experience only mild symptoms while others suffer fr…
Dual immunotherapy plus chemotherapy found to benefit specific subset of patients with lung cancer
Researchers from The University of Texas MD Anderson Cancer Center have demonstrated that patients with metastatic non-squamous non-small cell lung cancer (NSCLC) harboring specific mutations in the STK11 and/or KEAP1 tumor suppressor genes were more l…
Neural network models help predict immunotherapy efficacy in small cell lung cancer
As immunotherapy makes breakthrough progress in the treatment of small cell lung cancer (SCLC), predicting treatment outcomes has become a focal point in clinical practice. Immunotherapy combined with chemotherapy has been approved as first-line therap…
Researchers find cord blood cells can build a better human immune system into mice
Immunity plays a central role in the fight against cancer. Many of the current immunotherapies aim at helping the patient’s immune system to better recognize cancer cells—by using engineered antibodies—or by simply providing it with new cells, pre-equi…
Natural killer cells that live in the lungs can rapidly respond to a sugar rush, making them especially effective
Trinity College Dublin researchers based at St James’s Hospital have provided important insights into the behavior and metabolic function of a previously largely unknown but crucial natural killer (NK) immune cell resident in the lungs.
Exploring the cross-talk between innate and adaptive immunity
A new review by Dr. Ruyuan Wang and an international team of researchers explores the complex interactions between the innate and adaptive immune systems, shedding light on regulatory mechanisms in infection, cancer, and autoimmune diseases. Published …
Disrupting Asxl1 gene prevents T-cell exhaustion to improve immunotherapy, researchers discover
Immunotherapy, using a patient’s own immune system to treat disease, has shown promise in some patients with cancer but has not worked in most. New research from St. Jude Children’s Research Hospital and colleagues has found that disrupting Asxl1, a ge…
Urine albumin-to-creatinine ratio indicates risk in rheumatoid arthritis
For patients with rheumatoid arthritis (RA), urine albumin-to-creatinine ratio (ACR) is an independent risk factor indicating prognosis, according to a study published online Sept. 18 in Frontiers in Immunology.