Long COVID leaves telltale traces in the blood, finds new study
Findings from the largest UK study of patients hospitalized with SARS-CoV-2 infection show that long COVID leads to ongoing inflammation which can be detected in the blood.
Inmunología
Bispecific immune checkpoint inhibitor improves survival in gastric cancer patients regardless of PD-L1 status
The PD-1/CTLA-4 bispecific antibody cadonilimab plus chemotherapy improved progression-free survival and overall survival in patients with untreated, HER2-negative, locally advanced or metastatic gastric or gastroesophageal junction (GEJ) cancer, inclu…
Biologic drug-device combination immunotherapy for metastatic prostate cancer patients
SYNC-T, an investigational therapy that combines a device-induced vaccination at the tumor site with intratumoral infusion of a multitarget biologic drug led to numerous clinical responses in patients with metastatic castrate-resistant prostate cancer …
Researchers create guidelines to help kids build tolerance to food allergens
Researchers with McMaster University have crafted the first-ever guidelines to help prepare families who plan to build their child’s tolerance to common food allergens.
Immunotherapies show promise for patients with kidney cancer and solid organ transplant recipients with skin cancer
Researchers from The University of Texas MD Anderson Cancer Center presented encouraging findings from two clinical trials in a plenary session highlighting advances in novel immunotherapy approaches at the American Association for Cancer Research (AAC…
Targeting vulnerability in B-cell development leads to novel drug combination for leukemia
Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.
Rogue immune cell that can cause poor antibody responses in chronic viral infections discovered
Australian researchers have discovered a previously unknown rogue immune cell that can cause poor antibody responses in chronic viral infections. The finding, published in the journal, Immunity, may lead to earlier intervention and possibly prevention …
Study of twins provides new insights into immune defense in the womb
Niklas Björkström’s research group at the Department of Medicine, Huddinge (MedH) has conducted a study that provides new knowledge about how the immune system in the uterus works. This knowledge contributes to a better understanding of how pregnancy c…
EEG most beneficial tool for managing CAR T-cell-related neurotoxicity
For patients with immune effector cell-associated neurotoxicity syndrome (ICANS) due to chimeric antigen receptor (CAR) T-cell therapy, electroencephalogram (EEG) has the greatest therapeutic impact, according to a study published online March 19 in Bl…
Clinical trial data show investigational cancer vaccine may elicit lasting immune response in pancreatic cancer
New data presented by Memorial Sloan Kettering Cancer Center (MSK) researchers show an experimental approach to treating pancreatic cancer with the messenger RNA (mRNA)-based therapeutic cancer vaccine candidate, autogene cevumeran, continues to show p…