A pioneering clinical trial has successfully enabled two patients with end-stage kidney disease to receive previously improbable kidney transplants. These individuals were considered among the most difficult in the nation to match with a compatible don…
Researchers at Umeå University have shown in a new study that the environment in the womb can leave lasting imprints on the immune system and influence the risk of developing Type 1 diabetes, even when the genetic background is the same. The findings r…
Researchers at University Medical Center Utrecht have uncovered a previously underappreciated mechanism that helps immune cells to respond rapidly to infections. Using advanced long-read RNA sequencing, the team shows that alternative RNA splicing, whi…
T cells are some of the immune system’s most important warriors. They can stop tumor growth and even fight off severe infections. Now scientists at La Jolla Institute for Immunology (LJI) have discovered how T cells target paramyxoviruses, a viral fami…
Immune checkpoint therapy, a type of cancer immunotherapy that helps the immune system recognize and attack tumors, has transformed cancer treatment. While these therapies can produce long-lasting benefits for some patients, many cancers either fail to…
Researchers from VIB, VUB, and an international network of collaborators have created the most comprehensive single-cell atlas to date of tumor-associated dendritic cells. By integrating data from 14 mouse tumor models and 10 human cancer types, the st…
Our body receives and processes a vast number of signals. Chemical signals serve as guidance cues and ensure, for example, that immune cells arrive exactly where they are needed. Many vital processes such as sensory perception, immune responses, cardio…
A Salk Institute study found that a simple dietary amino acid, methionine, dramatically improved survival in mice facing severe infections and inflammatory conditions. Rather than directly targeting the immune system, methionine boosted kidney filtrati…
The combination of a vaccine and a drug, which both harness the immune system to attack cancer cells, has proven successful in cutting the risk of skin cancer recurrence and death by 49%, a new study shows. This reduction was calculated five years afte…
Microplastics (MP) are the subject of intensive medical research, but little is yet known about their effects on the immune system. A study led by the Medical University of Vienna now shows that tiny particles of polyethylene terephthalate (PET) remain…
