Researchers discover how immune B cells hunt down cancer around the body
Scientists have discovered the key features of immune B cells that make them successful at targeting tumors—including when cancer has spread to a different part of the body.
Noticias
Activation of innate immunity: Important piece of the puzzle identified
LMU researchers have deciphered the complex interplay of various enzymes around the innate immune receptor toll-like receptor 7 (TLR7), which plays an important role in defending our bodies against viruses.
Gene signatures from tissue-resident T cells as a predictive tool for melanoma patients
An extensive analytical study conducted at the Terasaki Institute for Biomedical Innovation (TIBI) has revealed an association between favorable survival outcomes for melanoma patients and the presence of higher populations of tissue-resident memory T …
Controlled human infection study paves the way to improving vaccines and therapeutics development
A first-of-its-kind study led by the University of Oxford has successfully investigated human immunity against COVID-19 in people who already have antibodies against it. The results suggest that previous infection, together with vaccination, offers str…
Skin patch improves treatment for pediatric milk allergies
Daily immunotherapy delivered via a dermal patch reduced the risk of reactions, including anaphylaxis, in children with an immunoglobulin E (IgE)–mediated cow’s milk allergy, according to a recent clinical trial published in JAMA Pediatrics.
Turning a tumor’s ‘shield’ into a weapon against itself
Tumor cells are “cunning,” according to Peter Yingxiao Wang. They have a nefarious way of evading the human immune responses that fight back against these cancerous invaders. Tumor cells express programmed death-ligand 1 (PD-L1) molecules, which work l…
Study reveals hidden diversity of innate immune cells
Findings from a new study, led by researchers at Dartmouth’s Geisel School of Medicine and published in Nature Immunology, have uncovered key functional differences in macrophages—a type of white blood cell that plays a pivotal role in the body’s innat…
New technique improves T cell-based immunotherapies for solid tumors
Scientists from Scripps Research have enhanced an existing immunotherapy by removing the sugar coating surrounding solid tumors—such as in melanoma, breast, and prostate cancer—so T cells can more effectively kill tumor cells. They report in the journa…
Experimental vaccine targets portions of the flu virus that don’t change
Duke researchers have opened a new avenue in the attack against influenza viruses by creating a vaccine that encourages the immune system to target a portion of the virus surface that is less variable.
New mRNA cancer vaccine triggers fierce immune response to fight malignant brain tumor
In a first-ever human clinical trial of four adult patients, an mRNA cancer vaccine developed at the University of Florida quickly reprogrammed the immune system to attack glioblastoma, the most aggressive and lethal brain tumor.