Stanford Medicine researchers and their colleagues found that a new drug, obexelimab, significantly reduces the risk of relapse in patients with IgG4-related disease, a rare chronic immune condition often misdiagnosed as cancer.
A consistent biological barrier that stops the immune system from making the antibodies most needed to protect the nose and throat from respiratory viruses has been identified. The discovery, led by researchers from the University of Surrey, in partner…
When thinking of the immune system, most people imagine white blood cells putting up a fight against invading germs in the bloodstream. But now, in research published in Molecular Cell, scientists detail a separate but equally important route by which …
Scientists have uncovered a surprising new way the immune system fights cancer, overturning a core belief that has guided immunology for decades. The research found that when cancer cells shut down a key immune-recognition molecule called MHC I—a commo…
Type 1 diabetes (T1D) is a lifelong autoimmune disorder where the immune system attacks islets, certain areas of the pancreas, and destroys cells that would otherwise produce insulin, a hormone crucial for regulating blood sugar levels. One emerging tr…
A pioneering clinical trial has successfully enabled two patients with end-stage kidney disease to receive previously improbable kidney transplants. These individuals were considered among the most difficult in the nation to match with a compatible don…
Researchers at Umeå University have shown in a new study that the environment in the womb can leave lasting imprints on the immune system and influence the risk of developing Type 1 diabetes, even when the genetic background is the same. The findings r…
Researchers at University Medical Center Utrecht have uncovered a previously underappreciated mechanism that helps immune cells to respond rapidly to infections. Using advanced long-read RNA sequencing, the team shows that alternative RNA splicing, whi…
T cells are some of the immune system’s most important warriors. They can stop tumor growth and even fight off severe infections. Now scientists at La Jolla Institute for Immunology (LJI) have discovered how T cells target paramyxoviruses, a viral fami…
Immune checkpoint therapy, a type of cancer immunotherapy that helps the immune system recognize and attack tumors, has transformed cancer treatment. While these therapies can produce long-lasting benefits for some patients, many cancers either fail to…
