Study uncovers a way to boost treatment for aggressive melanoma
A new study from researchers at Moffitt Cancer Center shows that blocking a chemical process called nitrosylation could make one of the most aggressive forms of melanoma more treatable.
Medical Xpress
Topical treatment offers relief from painful skin rash caused by targeted cancer therapy
Researchers from the UCLA Health Jonsson Comprehensive Cancer Center and The University of Texas MD Anderson Cancer Center have demonstrated that a novel topical BRAF inhibitor gel called LUT014 significantly reduces the severity of an acne-like rash, …
HER2 targeted therapy shows promise in previously treated lung cancers
The HER2-targeted therapy zongertinib demonstrated clinical benefits for previously treated patients with advanced HER2-mutant non-small cell lung cancer—particularly those with specific HER2 mutations—with manageable side effects, according to results…
Left or right arm? New research reveals why vaccination site matters for immune response
Sydney scientists have revealed why receiving a booster vaccine in the same arm as your first dose can generate a more effective immune response more quickly. The study, led by the Garvan Institute of Medical Research and the Kirby Institute at UNSW Sy…
Olaparib and pembrolizumab combination shows early promise in molecularly selected, tumor-agnostic trial
The combination of the PARP inhibitor olaparib and the PD-1 inhibitor pembrolizumab showed initial antitumor activity with no new safety signals in a molecularly matched, tumor-agnostic trial, particularly in patients with BRCA1/2 mutations, according …
Natural killer cells remember and effectively target ovarian cancer, researchers discover
Researchers at Karolinska Institutet have uncovered a unique ability of a special subtype of natural killer cells in the immune system, called adaptive NK cells, to remember ovarian tumors and effectively attack them. The discovery, published in Cancer…
Immunotherapy before and after surgery improves outcomes in head and neck cancer, clinical trial shows
Patients with locally advanced head and neck cancer who received the immune checkpoint inhibitor pembrolizumab before, during and after standard-of-care surgery had longer event-free survival without the cancer coming back and higher rates of substanti…
SENTI-202: Ready-made immune therapy found to be effective against leukemia
A ready-made version of a cutting-edge cancer immunotherapy can effectively defeat blood cancers, a new study says.
Aging reimagined: Study finds immune resilience counters key drivers of disease, mortality
What if, rather than focusing solely on the drivers of disease (pathogenesis), we also explored the factors sustaining our health—the concept of salutogenesis (derived from Salus (health) in Roman mythology)?
Brain’s immune response may set stage for childhood paralysis disorder
Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease, the brain appears to play a major role by over-activating t…