Newly-developed biomimetic materials can improve cancer immunotherapy
Researchers have developed novel lymph-node-inspired hydrogels that significantly enhance the activation, gene expression, and proliferation of CAR T cells.
Medical Xpress
Immune cell ‘messengers’ could save crumbling bones—new hope for joint pain sufferers
A recent study has uncovered a potential breakthrough in treating osteonecrosis of the femoral head (ONFH), a debilitating bone disease that causes severe pain and joint collapse. Researchers have discovered that exosomes derived from M2 macrophages-de…
Recently discovered immune cell type could be key to understanding food allergies
The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or “tolerate” molecules found in the body’s own healthy cells, for instance, as well…
New immune boost could expand access to cancer immunotherapy
Researchers at Moffitt Cancer Center have found that tapping into the body’s own immune system and activating a type of immune cell known as B cells, could be the key to boosting the effectiveness of tumor-infiltrating lymphocyte, or TIL therapy. Resul…
How one bad protein can affect both immunity and brain development
RIKEN researchers have discovered how a single mutation in one gene can simultaneously result in two symptoms—a severely compromised immune system and problems in brain development. Similar mechanisms may be at work in cancer and other genetic disorder…
Discovery of new immune response phase upends beliefs about T-cell priming
A team from the Max Planck Research Group for Systems Immunology at the University of Würzburg has identified a previously unknown phase of the immune response. The results, published in Science, challenge long-standing assumptions about the process ca…
Immune protein modification can curb viral replication and heart inflammation
Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication.
Immune-reactivating antibody therapy shows promise against ovarian cancer in new study
Research has shed light on how a new type of antibody treatment reactivates patients’ immune cells to fight ovarian cancer. The research, from the group of Professor Sophia Karagiannis at King’s College London, could help to better understand the respo…
Discovery of key mechanism could combat lenalidomide resistance in multiple myeloma
A new study conducted by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has uncovered a key mechanism behind lenalidomide resistance in multiple myeloma (MM), offering new insights int…
Fiber consumption protects gut from serious bacterial infection, study suggests
A study published in the journal Cell Host & Microbe by Brazilian and American researchers suggests that a diet rich in soluble fiber can protect the intestine against pathogenic bacteria.