Autoimmune pancreatitis (AIP) is a clinical condition characterized by inflammation of the pancreas, caused by the body’s hypersensitivity to its own proteins. AIP is typically accompanied by other organ inflammations such as autoimmune sialadenitis an…
In the fight against cancer, chimeric antigen receptor T cell (CAR-T) therapy has achieved notable success in treating blood cancers. However, it has been largely ineffective against solid tumors.
Multiple myeloma is a type of blood cancer that appears mainly after the age of 60. Its incidence, therefore, increases with the aging of the population. In this pathology, the bone marrow, the porous structure within the bones that produces normal blo…
Patients with a rare blood cancer that has relapsed or become resistant to treatment have shown a high response rate to a potent new immunotherapy drug, in a Peter Mac-led clinical trial.
Long COVID occurs in approximately a third of COVID-19 survivors, with the CDC estimating one in 13 adults in the United States have long COVID symptoms such as brain fog, shortness of breath and chest pain. In a new study published in Nature Immunolog…
Metastatic disease—when cancer spreads from the primary tumor to other parts of the body—is the cause of most cancer deaths. While researchers understand how cancer cells escape the primary site to seed new tumors, it’s not well understood why some of …
A new cell therapy, targeting CD7 in leukemia cells, gives a potentially effective treatment for patients with T-cell acute lymphoblastic leukemia (T-ALL) who have exhausted all standard treatment options. Published in the journal Nature Medicine on 3 …
Researchers at Karolinska Institutet and the University of Gothenburg have identified a biomarker that could become an important tool for health care in assessing patients with acute COVID-19 infection. The researchers have studied interleukin (IL)-26,…
A new study published in Cell Reports Medicine reveals critical insights into the role of gamma-delta T cells across 33 cancer types, shedding light on their potential as clinical biomarkers and therapeutic targets in cancer treatment. Led by a team of…
A new study, conducted in a shared effort between U.K. and Italian researchers offers novel insights about the biological mechanisms behind major depressive disorder (MDD), and especially on the role of the immune system.
