Chen, W., Liao, Y., Yao, H., Zou, Y., Fang, J., Zhang, J., Guo, Z., Tu, J., Chen, J., Huo, Z., Wen, L., Xie, X.

Multiomics integration analysis identifies tumor cell-derived MIF as a therapeutic target and potentiates anti-PD-1 therapy in osteosarcoma

22 de August de 2025 by Chen, W., Liao, Y., Yao, H., Zou, Y., Fang, J., Zhang, J., Guo, Z., Tu, J., Chen, J., Huo, Z., Wen, L., Xie, X.

Background
Osteosarcoma is a highly aggressive cancer, and the efficacy of existing therapies has plateaued. Multiomics integration analysis can identify novel therapeutic targets for various cancers and therefore shows potential toward osteosarcoma t…