Chen, X., Chen, J., Yin, Y., Sun, M., Li, S., Zhang, J., Wu, Z., Jiang, J., Hu, D., Fan, D., Nie, Y., Huang, W., Wu, K., Xia, L.

HOXD13-mediated immune crosstalk between cancer cells and tumor-associated macrophages drives colorectal cancer progression

24 de February de 2026 by Chen, X., Chen, J., Yin, Y., Sun, M., Li, S., Zhang, J., Wu, Z., Jiang, J., Hu, D., Fan, D., Nie, Y., Huang, W., Wu, K., Xia, L.

Background
The complex tumor microenvironment (TME) of colorectal cancer (CRC), composed of diverse cellular components and dynamic interactions, constitutes a major barrier to effective immunotherapy and facilitates disease progression. There is a pr…