Tong, Y., Chen, Z., Wu, J., Huang, Q., He, Y., Shang, H., Xia, D., Peng, E., Wang, Z., Liang, X., Tang, K.

METTL3 promotes an immunosuppressive microenvironment in bladder cancer via m6A-dependent CXCL5/CCL5 regulation

16 de April de 2025 by Tong, Y., Chen, Z., Wu, J., Huang, Q., He, Y., Shang, H., Xia, D., Peng, E., Wang, Z., Liang, X., Tang, K.

Background
Bladder cancer (BLCA) is a challenging malignancy with a poor prognosis, particularly in muscle-invasive cases. Despite recent advancements in immunotherapy, response rates remain suboptimal. This study investigates the role of METTL3, an m…