Macrophage NLRP3 activation and IL-1{beta} release drive osimertinib-induced antitumor immunity

Background
Despite the clinical efficacy of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) in non-small cell lung cancer (NSCLC), patient outcomes vary even among those with identical EGFR mutations. This study investigates wh…

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