Zhang, Y., Zheng, H., Zhang, R., Li, J., Yang, S., Hua, Y., Kleeff, J., Liao, Q., Liu, Q.

Pancreatic cancer cells escape T/NK cell immune surveillance through the expressional separation of CD58

15 de September de 2025 by Zhang, Y., Zheng, H., Zhang, R., Li, J., Yang, S., Hua, Y., Kleeff, J., Liao, Q., Liu, Q.

Background
Membrane (m) CD58 is a co-stimulatory ligand that binds to CD2, and the CD2-(m) CD58 axis participates in lymphocyte activation. In addition to mCD58, a soluble form of CD58 (sCD58) has been reported in human serum, urine, and in vitro cell…