Breastfeeding linked to lasting immune protection against breast cancer
A team of researchers led by Peter Mac’s Professor Sherene Loi has uncovered how having children and breastfeeding reduces a woman’s long-term risk of breast cancer.
Medical Xpress
Taking down malaria’s bodyguards: Scientists target parasite’s secret defense system
Malaria remains one of the world’s most devastating infectious diseases, claiming more than half a million lives each year. In Africa, the illness is mostly caused by a parasite carried by mosquitoes—Plasmodium falciparum.
Localized IL-12 delivery reshapes CAR-T safety in solid tumors
An international collaboration of researchers, including Imperial College London and UCLA, has developed a collagen-binding interleukin 12 strategy that lets CAR-T cells treat prostate cancer in mice while curbing previously encountered cytokine-relate…
Improving immunotherapy responses to fight cancer with dual therapies
Promising study in dual inhibition of PD1 and macrophage migration inhibitory factor
BiTE-based immunotherapy strategy could point the way to a breakthrough for ovarian cancer patients
Results of a study led by researchers at Roswell Park Comprehensive Cancer Center show that combining two types of immunotherapy—engineered T cells that secrete bispecific T cell engagers (BiTEs) and an immune checkpoint inhibitor—can alter the tumor m…
Influenza A-infected volunteers display different patterns of expelling viruses into environment
Late in the Middle Ages, Italian stargazers gave a name to the annual contagion that rolled around each year like clockwork. It was a name that stuck, and to this day is known as influenza.
Mitochondria and lysosomes reprogram immune cells that dampen inflammation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children’s Research Hospital scientists recently uncovered how mitochondria, the powerhouse of cells, a…
Researchers develop innovative vascularized tumor model to advance cancer immunotherapy
A research team led by the Faculty of Dentistry at The University of Hong Kong (HKU) has developed a novel vascularized tumor model using a non-surgical injectable hydrogel system. This innovative approach provides a powerful new platform for researchi…
Dual-function molecule could unlock smarter treatments for kidney disease
Chronic kidney disease (CKD) is a progressive condition in which the kidneys gradually lose their ability to filter waste from the blood. It is a common health concern that affects an estimated 8–16% of the global population, particularly among older a…
Immune-hot brain tumor subtype that defies survival expectations discovered
A research team has discovered a previously overlooked subtype of brain tumor termed IME IDH-mutant astrocytoma. Contrary to typical medical expectations, this subtype exhibits strong immune activity, classified as “immune‑hot,” yet tends to have poore…